Gu LQ - Search Results

1

A novel DNA topoisomerase I inhibitor with different mechanism from camptothecin induces G2/M phase cell cycle arrest to K562 cells.

Wu N, Wu XW, Agama K, Pommier Y, Du J, Li D, Gu LQ, Huang ZS, An LK. Wu N, et al. Among authors: gu lq. Biochemistry. 2010 Nov 30;49(47):10131-6. doi: 10.1021/bi1009419. Epub 2010 Nov 8. Biochemistry. 2010. PMID: 21033700 Free PMC article.

2

Synthesis, cytotoxic activities and structure-activity relationships of topoisomerase I inhibitors: indolizinoquinoline-5,12-dione derivatives.

Cheng Y, An LK, Wu N, Wang XD, Bu XZ, Huang ZS, Gu LQ. Cheng Y, et al. Among authors: gu lq. Bioorg Med Chem. 2008 Apr 15;16(8):4617-25. doi: 10.1016/j.bmc.2008.02.036. Epub 2008 Feb 15. Bioorg Med Chem. 2008. PMID: 18296054

3

Synthesis and antiproliferative activity of indolizinophthalazine-5,12-dione derivatives, DNA topoisomerase IB inhibitors.

Shen DQ, Wu ZP, Wu XW, An ZY, Bu XZ, Gu LQ, Huang ZS, An LK. Shen DQ, et al. Among authors: gu lq. Eur J Med Chem. 2010 Sep;45(9):3938-42. doi: 10.1016/j.ejmech.2010.05.048. Epub 2010 Jun 1. Eur J Med Chem. 2010. PMID: 20638158

4

Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II.

Zhuo ST, Li CY, Hu MH, Chen SB, Yao PF, Huang SL, Ou TM, Tan JH, An LK, Li D, Gu LQ, Huang ZS. Zhuo ST, et al. Among authors: gu lq. Org Biomol Chem. 2013 Jun 28;11(24):3989-4005. doi: 10.1039/c3ob40325d. Org Biomol Chem. 2013. PMID: 23657605

5

Synthesis and biological evaluation of 6-substituted indolizinoquinolinediones as catalytic DNA topoisomerase I inhibitors.

Yu LM, Zhang XR, Li XB, Yang Y, Wei HY, He XX, Gu LQ, Huang ZS, Pommier Y, An LK. Yu LM, et al. Among authors: gu lq. Eur J Med Chem. 2015 Aug 28;101:525-33. doi: 10.1016/j.ejmech.2015.07.007. Epub 2015 Jul 8. Eur J Med Chem. 2015. PMID: 26188908 Free PMC article.

6

Synthesis, cytotoxicity and structure-activity relationship of indolizinoquinolinedione derivatives as DNA topoisomerase IB catalytic inhibitors.

Yu Q, Yang H, Zhu TW, Yu LM, Chen JW, Gu LQ, Huang ZS, An LK. Yu Q, et al. Among authors: gu lq. Eur J Med Chem. 2018 May 25;152:195-207. doi: 10.1016/j.ejmech.2018.04.040. Epub 2018 Apr 22. Eur J Med Chem. 2018. PMID: 29705710

7

Oxoisoaporphine alkaloid derivatives: synthesis, DNA binding affinity and cytotoxicity.

Tang H, Wang XD, Wei YB, Huang SL, Huang ZS, Tan JH, An LK, Wu JY, Chan AS, Gu LQ. Tang H, et al. Among authors: gu lq. Eur J Med Chem. 2008 May;43(5):973-80. doi: 10.1016/j.ejmech.2007.07.004. Epub 2007 Jul 15. Eur J Med Chem. 2008. PMID: 17720282

8

Synthesis and evaluation of curcumin analogues as potential thioredoxin reductase inhibitors.

Qiu X, Liu Z, Shao WY, Liu X, Jing DP, Yu YJ, An LK, Huang SL, Bu XZ, Huang ZS, Gu LQ. Qiu X, et al. Among authors: gu lq. Bioorg Med Chem. 2008 Sep 1;16(17):8035-41. doi: 10.1016/j.bmc.2008.07.054. Epub 2008 Jul 24. Bioorg Med Chem. 2008. PMID: 18678491

9

Inhibition of thioredoxin reductase by curcumin analogs.

Liu Z, Du ZY, Huang ZS, Lee KS, Gu LQ. Liu Z, et al. Among authors: gu lq. Biosci Biotechnol Biochem. 2008 Aug;72(8):2214-8. doi: 10.1271/bbb.80229. Epub 2008 Aug 7. Biosci Biotechnol Biochem. 2008. PMID: 18685195 Free article.

10

Inhibition of thioredoxin reductase by mansonone F analogues: Implications for anticancer activity.

Liu Z, Huang SL, Li MM, Huang ZS, Lee KS, Gu LQ. Liu Z, et al. Among authors: gu lq. Chem Biol Interact. 2009 Jan 15;177(1):48-57. doi: 10.1016/j.cbi.2008.09.002. Epub 2008 Sep 7. Chem Biol Interact. 2009. PMID: 18822278

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