Blobel CP - Search Results

1

MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands.

Brandl K, Sun L, Neppl C, Siggs OM, Le Gall SM, Tomisato W, Li X, Du X, Maennel DN, Blobel CP, Beutler B. Brandl K, et al. Among authors: blobel cp. Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19967-72. doi: 10.1073/pnas.1014669107. Epub 2010 Nov 1. Proc Natl Acad Sci U S A. 2010. PMID: 21041656 Free PMC article.

2

The interferon-rich skin environment regulates Langerhans cell ADAM17 to promote photosensitivity in lupus.

Li TM, Zyulina V, Seltzer ES, Dacic M, Chinenov Y, Daamen AR, Veiga KR, Schwartz N, Oliver DJ, Cabahug-Zuckerman P, Lora J, Liu Y, Shipman WD, Ambler WG, Taber SF, Onel KB, Zippin JH, Rashighi M, Krueger JG, Anandasabapathy N, Rogatsky I, Jabbari A, Blobel CP, Lipsky PE, Lu TT. Li TM, et al. Among authors: blobel cp. Elife. 2024 Jun 11;13:e85914. doi: 10.7554/eLife.85914. Elife. 2024. PMID: 38860651 Free PMC article.

3

Substrate selectivity of epidermal growth factor-receptor ligand sheddases and their regulation by phorbol esters and calcium influx.

Horiuchi K, Le Gall S, Schulte M, Yamaguchi T, Reiss K, Murphy G, Toyama Y, Hartmann D, Saftig P, Blobel CP. Horiuchi K, et al. Among authors: blobel cp. Mol Biol Cell. 2007 Jan;18(1):176-88. doi: 10.1091/mbc.e06-01-0014. Epub 2006 Nov 1. Mol Biol Cell. 2007. PMID: 17079736 Free PMC article.

4

ADAMs 10 and 17 represent differentially regulated components of a general shedding machinery for membrane proteins such as transforming growth factor alpha, L-selectin, and tumor necrosis factor alpha.

Le Gall SM, Bobé P, Reiss K, Horiuchi K, Niu XD, Lundell D, Gibb DR, Conrad D, Saftig P, Blobel CP. Le Gall SM, et al. Among authors: blobel cp. Mol Biol Cell. 2009 Mar;20(6):1785-94. doi: 10.1091/mbc.e08-11-1135. Epub 2009 Jan 21. Mol Biol Cell. 2009. PMID: 19158376 Free PMC article.

5

Pathological neovascularization is reduced by inactivation of ADAM17 in endothelial cells but not in pericytes.

Weskamp G, Mendelson K, Swendeman S, Le Gall S, Ma Y, Lyman S, Hinoki A, Eguchi S, Guaiquil V, Horiuchi K, Blobel CP. Weskamp G, et al. Among authors: blobel cp. Circ Res. 2010 Mar 19;106(5):932-40. doi: 10.1161/CIRCRESAHA.109.207415. Epub 2010 Jan 28. Circ Res. 2010. PMID: 20110534 Free PMC article.

6

ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site.

Le Gall SM, Maretzky T, Issuree PD, Niu XD, Reiss K, Saftig P, Khokha R, Lundell D, Blobel CP. Le Gall SM, et al. Among authors: blobel cp. J Cell Sci. 2010 Nov 15;123(Pt 22):3913-22. doi: 10.1242/jcs.069997. Epub 2010 Oct 27. J Cell Sci. 2010. PMID: 20980382 Free PMC article.

7

Structural modeling defines transmembrane residues in ADAM17 that are crucial for Rhbdf2-ADAM17-dependent proteolysis.

Li X, Maretzky T, Perez-Aguilar JM, Monette S, Weskamp G, Le Gall S, Beutler B, Weinstein H, Blobel CP. Li X, et al. Among authors: blobel cp. J Cell Sci. 2017 Mar 1;130(5):868-878. doi: 10.1242/jcs.196436. Epub 2017 Jan 19. J Cell Sci. 2017. PMID: 28104813 Free PMC article.

8

Src stimulates fibroblast growth factor receptor-2 shedding by an ADAM15 splice variant linked to breast cancer.

Maretzky T, Le Gall SM, Worpenberg-Pietruk S, Eder J, Overall CM, Huang XY, Poghosyan Z, Edwards DR, Blobel CP. Maretzky T, et al. Among authors: blobel cp. Cancer Res. 2009 Jun 1;69(11):4573-6. doi: 10.1158/0008-5472.CAN-08-4766. Cancer Res. 2009. PMID: 19487280 Free article.

9

The cytoplasmic domain of a disintegrin and metalloproteinase 10 (ADAM10) regulates its constitutive activity but is dispensable for stimulated ADAM10-dependent shedding.

Maretzky T, Evers A, Le Gall S, Alabi RO, Speck N, Reiss K, Blobel CP. Maretzky T, et al. Among authors: blobel cp. J Biol Chem. 2015 Mar 20;290(12):7416-25. doi: 10.1074/jbc.M114.603753. Epub 2015 Jan 20. J Biol Chem. 2015. PMID: 25605720 Free PMC article.

10

iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling.

Li X, Maretzky T, Weskamp G, Monette S, Qing X, Issuree PD, Crawford HC, McIlwain DR, Mak TW, Salmon JE, Blobel CP. Li X, et al. Among authors: blobel cp. Proc Natl Acad Sci U S A. 2015 May 12;112(19):6080-5. doi: 10.1073/pnas.1505649112. Epub 2015 Apr 27. Proc Natl Acad Sci U S A. 2015. PMID: 25918388 Free PMC article.

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