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XIAP antisense oligonucleotide (AEG35156) achieves target knockdown and induces apoptosis preferentially in CD34+38- cells in a phase 1/2 study of patients with relapsed/refractory AML.
Carter BZ, Mak DH, Morris SJ, Borthakur G, Estey E, Byrd AL, Konopleva M, Kantarjian H, Andreeff M. Carter BZ, et al. Among authors: mak dh. Apoptosis. 2011 Jan;16(1):67-74. doi: 10.1007/s10495-010-0545-1. Apoptosis. 2011. PMID: 20938744 Free PMC article. Clinical Trial.
67 results