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213 results

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Page 1
The identification of novel orally active mGluR5 antagonist GSK2210875.
Pilla M, Andreoli M, Tessari M, Delle-Fratte S, Roth A, Butler S, Brown F, Shah P, Bettini E, Cavallini P, Benedetti R, Minick D, Smith P, Tehan B, D'Alessandro P, Lorthioir O, Ball C, Garzya V, Goodacre C, Watson S. Pilla M, et al. Among authors: benedetti r. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7521-4. doi: 10.1016/j.bmcl.2010.09.120. Epub 2010 Nov 2. Bioorg Med Chem Lett. 2010. PMID: 21051228
1-(Aryl)-6-[alkoxyalkyl]-3-azabicyclo[3.1.0]hexanes and 6-(aryl)-6-[alkoxyalkyl]-3-azabicyclo[3.1.0]hexanes: a new series of potent and selective triple reuptake inhibitors.
Micheli F, Cavanni P, Arban R, Benedetti R, Bertani B, Bettati M, Bettelini L, Bonanomi G, Braggio S, Checchia A, Davalli S, Di Fabio R, Fazzolari E, Fontana S, Marchioro C, Minick D, Negri M, Oliosi B, Read KD, Sartori I, Tedesco G, Tarsi L, Terreni S, Visentini F, Zocchi A, Zonzini L. Micheli F, et al. Among authors: benedetti r. J Med Chem. 2010 Mar 25;53(6):2534-51. doi: 10.1021/jm901818u. J Med Chem. 2010. PMID: 20170186
6-(3,4-dichlorophenyl)-1-[(methyloxy)methyl]-3-azabicyclo[4.1.0]heptane: a new potent and selective triple reuptake inhibitor.
Micheli F, Cavanni P, Andreotti D, Arban R, Benedetti R, Bertani B, Bettati M, Bettelini L, Bonanomi G, Braggio S, Carletti R, Checchia A, Corsi M, Fazzolari E, Fontana S, Marchioro C, Merlo-Pich E, Negri M, Oliosi B, Ratti E, Read KD, Roscic M, Sartori I, Spada S, Tedesco G, Tarsi L, Terreni S, Visentini F, Zocchi A, Zonzini L, Di Fabio R. Micheli F, et al. Among authors: benedetti r. J Med Chem. 2010 Jul 8;53(13):4989-5001. doi: 10.1021/jm100481d. J Med Chem. 2010. PMID: 20527970
Heteroaryl-substituted 4-(1H-pyrazol-1-yl)-5,6-dihydro-1H-pyrrolo[2,3-d]pyrimidine derivatives as potent and selective corticotropin-releasing factor receptor-1 antagonists.
Sabbatini FM, Di Fabio R, St-Denis Y, Capelli AM, Castiglioni E, Contini S, Donati D, Fazzolari E, Gentile G, Micheli F, Pavone F, Rinaldi M, Pasquarello A, Zampori MG, Di Felice P, Zarantonello P, Arban R, Perini B, Vitulli G, Benedetti R, Oliosi B, Worby A. Sabbatini FM, et al. Among authors: benedetti r. ChemMedChem. 2008 Feb;3(2):226-9. doi: 10.1002/cmdc.200700230. ChemMedChem. 2008. PMID: 18000940 No abstract available.
Cyclopenta[d]pyrimidines and dihydropyrrolo[2,3-d]pyrimidines as potent and selective corticotropin-releasing factor 1 receptor antagonists.
Arban R, Benedetti R, Bonanomi G, Capelli AM, Castiglioni E, Contini S, Degiorgis F, Di Felice P, Donati D, Fazzolari E, Gentile G, Marchionni C, Marchioro C, Messina F, Micheli F, Oliosi B, Pavone F, Pasquarello A, Perini B, Rinaldi M, Sabbatini FM, Vitulli G, Zarantonello P, Di Fabio R, St-Denis Y. Arban R, et al. Among authors: benedetti r. ChemMedChem. 2007 Apr;2(4):528-40. doi: 10.1002/cmdc.200600257. ChemMedChem. 2007. PMID: 17335099
Unlocking the power of empagliflozin: Rescuing inflammation in hyperglycaemia- exposed human cardiomyocytes through comprehensive multi-level analysis.
Benedetti R, Chianese U, Papulino C, Scisciola L, Cortese M, Formisano P, Del Gaudio N, Cabaro S, D'Esposito V, Pesapane A, Conte M, Signoriello G, Barbieri M, Altucci L, Paolisso G. Benedetti R, et al. Eur J Heart Fail. 2025 Jan 14. doi: 10.1002/ejhf.3566. Online ahead of print. Eur J Heart Fail. 2025. PMID: 39809551
213 results