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Page 1
Synthesis and pharmacological evaluation of the stereoisomers of 3-carba cyclic-phosphatidic acid.
Gupte R, Siddam A, Lu Y, Li W, Fujiwara Y, Panupinthu N, Pham TC, Baker DL, Parrill AL, Gotoh M, Murakami-Murofushi K, Kobayashi S, Mills GB, Tigyi G, Miller DD. Gupte R, et al. Among authors: pham tc. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7525-8. doi: 10.1016/j.bmcl.2010.09.115. Epub 2010 Oct 8. Bioorg Med Chem Lett. 2010. PMID: 21051230 Free PMC article.
(S)-FTY720-vinylphosphonate, an analogue of the immunosuppressive agent FTY720, is a pan-antagonist of sphingosine 1-phosphate GPCR signaling and inhibits autotaxin activity.
Valentine WJ, Kiss GN, Liu J, E S, Gotoh M, Murakami-Murofushi K, Pham TC, Baker DL, Parrill AL, Lu X, Sun C, Bittman R, Pyne NJ, Tigyi G. Valentine WJ, et al. Among authors: pham tc. Cell Signal. 2010 Oct;22(10):1543-53. doi: 10.1016/j.cellsig.2010.05.023. Epub 2010 Jun 4. Cell Signal. 2010. PMID: 20566326 Free PMC article.
Targeting the hydrophobic pocket of autotaxin with virtual screening of inhibitors identifies a common aromatic sulfonamide structural motif.
Fells JI, Lee SC, Norman DD, Tsukahara R, Kirby JR, Nelson S, Seibel W, Papoian R, Patil R, Miller DD, Parrill AL, Pham TC, Baker DL, Bittman R, Tigyi G. Fells JI, et al. Among authors: pham tc. FEBS J. 2014 Feb;281(4):1017-28. doi: 10.1111/febs.12674. Epub 2014 Jan 15. FEBS J. 2014. PMID: 24314137 Free PMC article.
The mitochondrial mRNA-stabilizing protein SLIRP regulates skeletal muscle mitochondrial structure and respiration by exercise-recoverable mechanisms.
Pham TCP, Raun SH, Havula E, Henriquez-Olguín C, Rubalcava-Gracia D, Frank E, Fritzen AM, Jannig PR, Andersen NR, Kruse R, Ali MS, Irazoki A, Halling JF, Ringholm S, Needham EJ, Hansen S, Lemminger AK, Schjerling P, Petersen MH, de Almeida ME, Jensen TE, Kiens B, Hostrup M, Larsen S, Ørtenblad N, Højlund K, Kjær M, Ruas JL, Trifunovic A, Wojtaszewski JFP, Nielsen J, Qvortrup K, Pilegaard H, Richter EA, Sylow L. Pham TCP, et al. Nat Commun. 2024 Nov 13;15(1):9826. doi: 10.1038/s41467-024-54183-4. Nat Commun. 2024. PMID: 39537626 Free PMC article.
Dual anticancer and antibacterial activity of fluorescent naphthoimidazolium salts.
Tran DN, Hoang TTH, Nandanwar S, Ho VTTX, Pham VT, Vu HD, Nguyen XH, Nguyen HT, Nguyen TV, Nguyen TKV, Tran DL, Park M, Lee S, Pham TC. Tran DN, et al. Among authors: pham tc. RSC Adv. 2023 Dec 14;13(51):36430-36438. doi: 10.1039/d3ra06555c. eCollection 2023 Dec 8. RSC Adv. 2023. PMID: 38099251 Free PMC article.
TNIK is a conserved regulator of glucose and lipid metabolism in obesity.
Pham TCP, Dollet L, Ali MS, Raun SH, Møller LLV, Jafari A, Ditzel N, Andersen NR, Fritzen AM, Gerhart-Hines Z, Kiens B, Suomalainen A, Simpson SJ, Salling Olsen M, Kieser A, Schjerling P, Nieminen AI, Richter EA, Havula E, Sylow L. Pham TCP, et al. Sci Adv. 2023 Aug 9;9(32):eadf7119. doi: 10.1126/sciadv.adf7119. Epub 2023 Aug 9. Sci Adv. 2023. PMID: 37556547 Free PMC article.
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