Peterson JR - Search Results

1

Phosphoinositides are essential coactivators for p21-activated kinase 1.

Strochlic TI, Viaud J, Rennefahrt UE, Anastassiadis T, Peterson JR. Strochlic TI, et al. Among authors: peterson jr. Mol Cell. 2010 Nov 12;40(3):493-500. doi: 10.1016/j.molcel.2010.10.015. Mol Cell. 2010. PMID: 21070974 Free PMC article.

2

An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase.

Deacon SW, Beeser A, Fukui JA, Rennefahrt UE, Myers C, Chernoff J, Peterson JR. Deacon SW, et al. Among authors: peterson jr. Chem Biol. 2008 Apr;15(4):322-31. doi: 10.1016/j.chembiol.2008.03.005. Chem Biol. 2008. PMID: 18420139 Free PMC article.

3

An allosteric kinase inhibitor binds the p21-activated kinase autoregulatory domain covalently.

Viaud J, Peterson JR. Viaud J, et al. Among authors: peterson jr. Mol Cancer Ther. 2009 Sep;8(9):2559-65. doi: 10.1158/1535-7163.MCT-09-0102. Epub 2009 Sep 1. Mol Cancer Ther. 2009. PMID: 19723886 Free PMC article.

4

Identification of allosteric inhibitors of p21-activated kinase.

Viaud J, Peterson JR. Viaud J, et al. Among authors: peterson jr. Methods Mol Biol. 2012;928:67-79. doi: 10.1007/978-1-62703-008-3_6. Methods Mol Biol. 2012. PMID: 22956134

5

Specificity profiling of Pak kinases allows identification of novel phosphorylation sites.

Rennefahrt UE, Deacon SW, Parker SA, Devarajan K, Beeser A, Chernoff J, Knapp S, Turk BE, Peterson JR. Rennefahrt UE, et al. Among authors: peterson jr. J Biol Chem. 2007 May 25;282(21):15667-78. doi: 10.1074/jbc.M700253200. Epub 2007 Mar 28. J Biol Chem. 2007. PMID: 17392278 Free article.

6

Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.

Anastassiadis T, Deacon SW, Devarajan K, Ma H, Peterson JR. Anastassiadis T, et al. Among authors: peterson jr. Nat Biotechnol. 2011 Oct 30;29(11):1039-45. doi: 10.1038/nbt.2017. Nat Biotechnol. 2011. PMID: 22037377 Free PMC article.

7

Identification of neuronal substrates implicates Pak5 in synaptic vesicle trafficking.

Strochlic TI, Concilio S, Viaud J, Eberwine RA, Wong LE, Minden A, Turk BE, Plomann M, Peterson JR. Strochlic TI, et al. Among authors: peterson jr. Proc Natl Acad Sci U S A. 2012 Mar 13;109(11):4116-21. doi: 10.1073/pnas.1116560109. Epub 2012 Feb 27. Proc Natl Acad Sci U S A. 2012. PMID: 22371566 Free PMC article.

8

Ack kinase regulates CTP synthase filaments during Drosophila oogenesis.

Strochlic TI, Stavrides KP, Thomas SV, Nicolas E, O'Reilly AM, Peterson JR. Strochlic TI, et al. Among authors: peterson jr. EMBO Rep. 2014 Nov;15(11):1184-91. doi: 10.15252/embr.201438688. Epub 2014 Sep 15. EMBO Rep. 2014. PMID: 25223282 Free PMC article.

9

A highly selective dual insulin receptor (IR)/insulin-like growth factor 1 receptor (IGF-1R) inhibitor derived from an extracellular signal-regulated kinase (ERK) inhibitor.

Anastassiadis T, Duong-Ly KC, Deacon SW, Lafontant A, Ma H, Devarajan K, Dunbrack RL Jr, Wu J, Peterson JR. Anastassiadis T, et al. Among authors: peterson jr. J Biol Chem. 2013 Sep 27;288(39):28068-77. doi: 10.1074/jbc.M113.505032. Epub 2013 Aug 9. J Biol Chem. 2013. PMID: 23935097 Free PMC article.

10

Synergistic activation of p21-activated kinase 1 by phosphatidylinositol 4,5-bisphosphate and Rho GTPases.

Malecka KA, Szentpetery Z, Peterson JR. Malecka KA, et al. Among authors: peterson jr. J Biol Chem. 2013 Mar 29;288(13):8887-97. doi: 10.1074/jbc.M112.428904. Epub 2013 Feb 7. J Biol Chem. 2013. PMID: 23393142 Free PMC article.

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