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Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway.
Jagani Z, Mora-Blanco EL, Sansam CG, McKenna ES, Wilson B, Chen D, Klekota J, Tamayo P, Nguyen PT, Tolstorukov M, Park PJ, Cho YJ, Hsiao K, Buonamici S, Pomeroy SL, Mesirov JP, Ruffner H, Bouwmeester T, Luchansky SJ, Murtie J, Kelleher JF, Warmuth M, Sellers WR, Roberts CW, Dorsch M. Jagani Z, et al. Among authors: sansam cg. Nat Med. 2010 Dec;16(12):1429-33. doi: 10.1038/nm.2251. Epub 2010 Nov 14. Nat Med. 2010. PMID: 21076395 Free PMC article.
Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformation.
Isakoff MS, Sansam CG, Tamayo P, Subramanian A, Evans JA, Fillmore CM, Wang X, Biegel JA, Pomeroy SL, Mesirov JP, Roberts CW. Isakoff MS, et al. Among authors: sansam cg. Proc Natl Acad Sci U S A. 2005 Dec 6;102(49):17745-50. doi: 10.1073/pnas.0509014102. Epub 2005 Nov 21. Proc Natl Acad Sci U S A. 2005. PMID: 16301525 Free PMC article.
TCR-dependent transformation of mature memory phenotype T cells in mice.
Wang X, Werneck MB, Wilson BG, Kim HJ, Kluk MJ, Thom CS, Wischhusen JW, Evans JA, Jesneck JL, Nguyen P, Sansam CG, Cantor H, Roberts CW. Wang X, et al. Among authors: sansam cg. J Clin Invest. 2011 Oct;121(10):3834-45. doi: 10.1172/JCI37210. Epub 2011 Sep 19. J Clin Invest. 2011. PMID: 21926465 Free PMC article.
Esco1 and Esco2 regulate distinct cohesin functions during cell cycle progression.
Alomer RM, da Silva EML, Chen J, Piekarz KM, McDonald K, Sansam CG, Sansam CL, Rankin S. Alomer RM, et al. Among authors: sansam cg. Proc Natl Acad Sci U S A. 2017 Sep 12;114(37):9906-9911. doi: 10.1073/pnas.1708291114. Epub 2017 Aug 28. Proc Natl Acad Sci U S A. 2017. PMID: 28847955 Free PMC article.
17 results