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N- and O-methylation of sphingomyelin markedly affects its membrane properties and interactions with cholesterol.
Björkbom A, Róg T, Kankaanpää P, Lindroos D, Kaszuba K, Kurita M, Yamaguchi S, Yamamoto T, Jaikishan S, Paavolainen L, Päivärinne J, Nyholm TK, Katsumura S, Vattulainen I, Slotte JP. Björkbom A, et al. Among authors: katsumura s. Biochim Biophys Acta. 2011 Apr;1808(4):1179-86. doi: 10.1016/j.bbamem.2011.01.009. Epub 2011 Jan 22. Biochim Biophys Acta. 2011. PMID: 21262197 Free article.
2NH and 3OH are crucial structural requirements in sphingomyelin for sticholysin II binding and pore formation in bilayer membranes.
Maula T, Isaksson YJ, García-Linares S, Niinivehmas S, Pentikäinen OT, Kurita M, Yamaguchi S, Yamamoto T, Katsumura S, Gavilanes JG, Martínez-del-Pozo A, Slotte JP. Maula T, et al. Among authors: katsumura s. Biochim Biophys Acta. 2013 May;1828(5):1390-5. doi: 10.1016/j.bbamem.2013.01.018. Epub 2013 Jan 30. Biochim Biophys Acta. 2013. PMID: 23376330 Free article.
95 results