Organ MG - Search Results

1

Thermodynamic and NMR analysis of inhibitor binding to dihydrofolate reductase.

Batruch I, Javasky E, Brown ED, Organ MG, Johnson PE. Batruch I, et al. Among authors: organ mg. Bioorg Med Chem. 2010 Dec 15;18(24):8485-92. doi: 10.1016/j.bmc.2010.10.048. Epub 2010 Oct 26. Bioorg Med Chem. 2010. PMID: 21084197

2

An expedient and facile one-step synthesis of a biguanide library by microwave irradiation coupled with simple product filtration. Inhibitors of dihydrofolate reductase.

Mayer S, Daigle DM, Brown ED, Khatri J, Organ MG. Mayer S, et al. Among authors: organ mg. J Comb Chem. 2004 Sep-Oct;6(5):776-82. doi: 10.1021/cc049953+. J Comb Chem. 2004. PMID: 15360213

3

A 2.13 A structure of E. coli dihydrofolate reductase bound to a novel competitive inhibitor reveals a new binding surface involving the M20 loop region.

Summerfield RL, Daigle DM, Mayer S, Mallik D, Hughes DW, Jackson SG, Sulek M, Organ MG, Brown ED, Junop MS. Summerfield RL, et al. Among authors: organ mg. J Med Chem. 2006 Nov 30;49(24):6977-86. doi: 10.1021/jm060570v. J Med Chem. 2006. PMID: 17125251

4

Quantitative affinity electrophoresis of RNA-small molecule interactions by cross-linking the ligand to acrylamide.

Boodram SN, McCann LC, Organ MG, Johnson PE. Boodram SN, et al. Among authors: organ mg. Anal Biochem. 2013 Nov 15;442(2):231-6. doi: 10.1016/j.ab.2013.07.040. Epub 2013 Aug 6. Anal Biochem. 2013. PMID: 23928050

5

Discovery of an antivirulence compound that reverses β-lactam resistance in MRSA.

El-Halfawy OM, Czarny TL, Flannagan RS, Day J, Bozelli JC Jr, Kuiack RC, Salim A, Eckert P, Epand RM, McGavin MJ, Organ MG, Heinrichs DE, Brown ED. El-Halfawy OM, et al. Among authors: organ mg. Nat Chem Biol. 2020 Feb;16(2):143-149. doi: 10.1038/s41589-019-0401-8. Epub 2019 Nov 25. Nat Chem Biol. 2020. PMID: 31768032

6

Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria.

Workman SD, Day J, Farha MA, El Zahed SS, Bon C, Brown ED, Organ MG, Strynadka NCJ. Workman SD, et al. Among authors: organ mg. J Med Chem. 2021 Sep 23;64(18):13540-13550. doi: 10.1021/acs.jmedchem.1c00941. Epub 2021 Sep 2. J Med Chem. 2021. PMID: 34473495

7

Synthesis of stereodefined polysubstituted olefins. 1. Sequential intermolecular reactions involving selective, stepwise insertion of Pd(0) into allylic and vinylic halide bonds. The stereoselective synthesis of disubstituted olefins.

Organ MG, Cooper JT, Rogers LR, Soleymanzadeh F, Paul T. Organ MG, et al. J Org Chem. 2000 Nov 17;65(23):7959-70. doi: 10.1021/jo001045l. J Org Chem. 2000. PMID: 11073604

8

The synthesis of deoxyfusapyrone. 2. Preparation of the bis-trisubstituted olefin fragment and its attachment to the pyrone moiety.

Organ MG, Wang J. Organ MG, et al. J Org Chem. 2003 Jul 11;68(14):5568-74. doi: 10.1021/jo034371k. J Org Chem. 2003. PMID: 12839448

9

Solution phase synthesis of libraries of variably substituted olefin scaffolds: a library of allylic amines.

Organ MG, Mayhew D, Cooper JT, Dixon CE, Lavorato DJ, Kaldor SW, Siegel MG. Organ MG, et al. J Comb Chem. 2001 Jan-Feb;3(1):64-7. doi: 10.1021/cc0000601. J Comb Chem. 2001. PMID: 11148064

10

Solution-phase synthesis of an aminomethyl-substituted biaryl library via sequential amine N-alkylation and Suzuki cross-coupling.

Organ MG, Arvanitis EA, Dixon CE, Lavorato DJ. Organ MG, et al. J Comb Chem. 2001 Sep-Oct;3(5):473-6. doi: 10.1021/cc010018l. J Comb Chem. 2001. PMID: 11549366

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

127 results

Search Page

Filters