Guan KL - Search Results

1

Generation of acetyllysine antibodies and affinity enrichment of acetylated peptides.

Guan KL, Yu W, Lin Y, Xiong Y, Zhao S. Guan KL, et al. Nat Protoc. 2010 Sep;5(9):1583-95. doi: 10.1038/nprot.2010.117. Epub 2010 Sep 2. Nat Protoc. 2010. PMID: 21085124 Free PMC article.

2

A role for NF-kappaB essential modifier/IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha.

Tang ED, Wang CY, Xiong Y, Guan KL. Tang ED, et al. Among authors: guan kl. J Biol Chem. 2003 Sep 26;278(39):37297-305. doi: 10.1074/jbc.M303389200. Epub 2003 Jul 16. J Biol Chem. 2003. PMID: 12867425 Free article.

3

TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway.

Lei QY, Zhang H, Zhao B, Zha ZY, Bai F, Pei XH, Zhao S, Xiong Y, Guan KL. Lei QY, et al. Among authors: guan kl. Mol Cell Biol. 2008 Apr;28(7):2426-36. doi: 10.1128/MCB.01874-07. Epub 2008 Jan 28. Mol Cell Biol. 2008. PMID: 18227151 Free PMC article.

4

Substrate selectivity APPLies to Akt.

Zhao S, Guan KL. Zhao S, et al. Among authors: guan kl. Cell. 2008 May 2;133(3):399-400. doi: 10.1016/j.cell.2008.04.015. Cell. 2008. PMID: 18455980 Free article.

5

Lysine 88 acetylation negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals.

Yu W, Lin Y, Yao J, Huang W, Lei Q, Xiong Y, Zhao S, Guan KL. Yu W, et al. Among authors: guan kl. J Biol Chem. 2009 May 15;284(20):13669-13675. doi: 10.1074/jbc.M901921200. Epub 2009 Mar 23. J Biol Chem. 2009. PMID: 19318352 Free PMC article.

6

TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition.

Zhang H, Liu CY, Zha ZY, Zhao B, Yao J, Zhao S, Xiong Y, Lei QY, Guan KL. Zhang H, et al. Among authors: guan kl. J Biol Chem. 2009 May 15;284(20):13355-13362. doi: 10.1074/jbc.M900843200. Epub 2009 Mar 26. J Biol Chem. 2009. PMID: 19324877 Free PMC article.

7

Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha.

Zhao S, Lin Y, Xu W, Jiang W, Zha Z, Wang P, Yu W, Li Z, Gong L, Peng Y, Ding J, Lei Q, Guan KL, Xiong Y. Zhao S, et al. Among authors: guan kl. Science. 2009 Apr 10;324(5924):261-5. doi: 10.1126/science.1170944. Science. 2009. PMID: 19359588 Free PMC article.

8

Regulation of cellular metabolism by protein lysine acetylation.

Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL. Zhao S, et al. Among authors: guan kl. Science. 2010 Feb 19;327(5968):1000-4. doi: 10.1126/science.1179689. Science. 2010. PMID: 20167786 Free PMC article.

9

Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux.

Wang Q, Zhang Y, Yang C, Xiong H, Lin Y, Yao J, Li H, Xie L, Zhao W, Yao Y, Ning ZB, Zeng R, Xiong Y, Guan KL, Zhao S, Zhao GP. Wang Q, et al. Among authors: guan kl. Science. 2010 Feb 19;327(5968):1004-7. doi: 10.1126/science.1179687. Science. 2010. PMID: 20167787 Free PMC article.

10

The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCF{beta}-TrCP E3 ligase.

Liu CY, Zha ZY, Zhou X, Zhang H, Huang W, Zhao D, Li T, Chan SW, Lim CJ, Hong W, Zhao S, Xiong Y, Lei QY, Guan KL. Liu CY, et al. Among authors: guan kl. J Biol Chem. 2010 Nov 26;285(48):37159-69. doi: 10.1074/jbc.M110.152942. Epub 2010 Sep 21. J Biol Chem. 2010. PMID: 20858893 Free PMC article.

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