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Transcription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis.
Lacroix M, Caramel J, Goguet-Rubio P, Linares LK, Estrach S, Hatchi E, Rodier G, Lledo G, de Bettignies C, Thépot A, Deraison C, Chébli K, Hovnanian A, Hainaut P, Dubus P, Sardet C, Le Cam L. Lacroix M, et al. Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):21076-81. doi: 10.1073/pnas.1010167107. Epub 2010 Nov 18. Proc Natl Acad Sci U S A. 2010. PMID: 21088222 Free PMC article.
The LIM-only protein FHL2 is a negative regulator of E4F1.
Paul C, Lacroix M, Iankova I, Julien E, Schäfer BW, Labalette C, Wei Y, Le Cam A, Le Cam L, Sardet C. Paul C, et al. Among authors: lacroix m. Oncogene. 2006 Sep 7;25(40):5475-84. doi: 10.1038/sj.onc.1209567. Epub 2006 May 1. Oncogene. 2006. PMID: 16652157
Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing.
Bonnart C, Deraison C, Lacroix M, Uchida Y, Besson C, Robin A, Briot A, Gonthier M, Lamant L, Dubus P, Monsarrat B, Hovnanian A. Bonnart C, et al. Among authors: lacroix m. J Clin Invest. 2010 Mar;120(3):871-82. doi: 10.1172/JCI41440. Epub 2010 Feb 22. J Clin Invest. 2010. PMID: 20179351 Free PMC article.
621 results