Lee H - Search Results

1

STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors.

Lee H, Deng J, Kujawski M, Yang C, Liu Y, Herrmann A, Kortylewski M, Horne D, Somlo G, Forman S, Jove R, Yu H. Lee H, et al. Nat Med. 2010 Dec;16(12):1421-8. doi: 10.1038/nm.2250. Epub 2010 Nov 21. Nat Med. 2010. PMID: 21102457 Free PMC article.

2

Stat3 mediates myeloid cell-dependent tumor angiogenesis in mice.

Kujawski M, Kortylewski M, Lee H, Herrmann A, Kay H, Yu H. Kujawski M, et al. Among authors: lee h. J Clin Invest. 2008 Oct;118(10):3367-77. doi: 10.1172/JCI35213. J Clin Invest. 2008. PMID: 18776941 Free PMC article.

3

Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment.

Kortylewski M, Xin H, Kujawski M, Lee H, Liu Y, Harris T, Drake C, Pardoll D, Yu H. Kortylewski M, et al. Among authors: lee h. Cancer Cell. 2009 Feb 3;15(2):114-23. doi: 10.1016/j.ccr.2008.12.018. Cancer Cell. 2009. PMID: 19185846 Free PMC article.

4

Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors.

Lee H, Herrmann A, Deng JH, Kujawski M, Niu G, Li Z, Forman S, Jove R, Pardoll DM, Yu H. Lee H, et al. Cancer Cell. 2009 Apr 7;15(4):283-93. doi: 10.1016/j.ccr.2009.02.015. Cancer Cell. 2009. PMID: 19345327 Free PMC article.

5

In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses.

Kortylewski M, Swiderski P, Herrmann A, Wang L, Kowolik C, Kujawski M, Lee H, Scuto A, Liu Y, Yang C, Deng J, Soifer HS, Raubitschek A, Forman S, Rossi JJ, Pardoll DM, Jove R, Yu H. Kortylewski M, et al. Among authors: lee h. Nat Biotechnol. 2009 Oct;27(10):925-32. doi: 10.1038/nbt.1564. Epub 2009 Sep 13. Nat Biotechnol. 2009. PMID: 19749770 Free PMC article.

6

A requirement of STAT3 DNA binding precludes Th-1 immunostimulatory gene expression by NF-κB in tumors.

Lee H, Deng J, Xin H, Liu Y, Pardoll D, Yu H. Lee H, et al. Cancer Res. 2011 Jun 1;71(11):3772-80. doi: 10.1158/0008-5472.CAN-10-3304. Epub 2011 Apr 18. Cancer Res. 2011. PMID: 21502401 Free PMC article.

7

Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation.

Lee H, Zhang P, Herrmann A, Yang C, Xin H, Wang Z, Hoon DS, Forman SJ, Jove R, Riggs AD, Yu H. Lee H, et al. Proc Natl Acad Sci U S A. 2012 May 15;109(20):7765-9. doi: 10.1073/pnas.1205132109. Epub 2012 Apr 30. Proc Natl Acad Sci U S A. 2012. PMID: 22547799 Free PMC article.

8

S1PR1-STAT3 signaling is crucial for myeloid cell colonization at future metastatic sites.

Deng J, Liu Y, Lee H, Herrmann A, Zhang W, Zhang C, Shen S, Priceman SJ, Kujawski M, Pal SK, Raubitschek A, Hoon DSB, Forman S, Figlin RA, Liu J, Jove R, Yu H. Deng J, et al. Among authors: lee h. Cancer Cell. 2012 May 15;21(5):642-654. doi: 10.1016/j.ccr.2012.03.039. Cancer Cell. 2012. PMID: 22624714 Free PMC article.

9

S1PR1 is an effective target to block STAT3 signaling in activated B cell-like diffuse large B-cell lymphoma.

Liu Y, Deng J, Wang L, Lee H, Armstrong B, Scuto A, Kowolik C, Weiss LM, Forman S, Yu H. Liu Y, et al. Among authors: lee h. Blood. 2012 Aug 16;120(7):1458-65. doi: 10.1182/blood-2011-12-399030. Epub 2012 Jun 28. Blood. 2012. PMID: 22745305 Free PMC article.

10

G-protein-coupled receptor agonist BV8/prokineticin-2 and STAT3 protein form a feed-forward loop in both normal and malignant myeloid cells.

Xin H, Lu R, Lee H, Zhang W, Zhang C, Deng J, Liu Y, Shen S, Wagner KU, Forman S, Jove R, Yu H. Xin H, et al. Among authors: lee h. J Biol Chem. 2013 May 10;288(19):13842-9. doi: 10.1074/jbc.M113.450049. Epub 2013 Apr 2. J Biol Chem. 2013. PMID: 23548897 Free PMC article.

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