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Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance.
Lee HY, Choi CS, Birkenfeld AL, Alves TC, Jornayvaz FR, Jurczak MJ, Zhang D, Woo DK, Shadel GS, Ladiges W, Rabinovitch PS, Santos JH, Petersen KF, Samuel VT, Shulman GI. Lee HY, et al. Among authors: rabinovitch ps. Cell Metab. 2010 Dec 1;12(6):668-74. doi: 10.1016/j.cmet.2010.11.004. Cell Metab. 2010. PMID: 21109199 Free PMC article.
Overexpression of catalase targeted to mitochondria attenuates murine cardiac aging.
Dai DF, Santana LF, Vermulst M, Tomazela DM, Emond MJ, MacCoss MJ, Gollahon K, Martin GM, Loeb LA, Ladiges WC, Rabinovitch PS. Dai DF, et al. Among authors: rabinovitch ps. Circulation. 2009 Jun 2;119(21):2789-97. doi: 10.1161/CIRCULATIONAHA.108.822403. Epub 2009 May 18. Circulation. 2009. PMID: 19451351 Free PMC article.
Extension of murine life span by overexpression of catalase targeted to mitochondria.
Schriner SE, Linford NJ, Martin GM, Treuting P, Ogburn CE, Emond M, Coskun PE, Ladiges W, Wolf N, Van Remmen H, Wallace DC, Rabinovitch PS. Schriner SE, et al. Among authors: rabinovitch ps. Science. 2005 Jun 24;308(5730):1909-11. doi: 10.1126/science.1106653. Epub 2005 May 5. Science. 2005. PMID: 15879174
Lifespan extension in genetically modified mice.
Ladiges W, Van Remmen H, Strong R, Ikeno Y, Treuting P, Rabinovitch P, Richardson A. Ladiges W, et al. Aging Cell. 2009 Aug;8(4):346-52. doi: 10.1111/j.1474-9726.2009.00491.x. Epub 2009 May 22. Aging Cell. 2009. PMID: 19485964 Free article. Review.
337 results