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In vitro anticancer activity, toxicity and structure-activity relationships of phyllostictine A, a natural oxazatricycloalkenone produced by the fungus Phyllosticta cirsii.
Le Calvé B, Lallemand B, Perrone C, Lenglet G, Depauw S, Van Goietsenoven G, Bury M, Vurro M, Herphelin F, Andolfi A, Zonno MC, Mathieu V, Dufrasne F, Van Antwerpen P, Poumay Y, David-Cordonnier MH, Evidente A, Kiss R. Le Calvé B, et al. Among authors: andolfi a. Toxicol Appl Pharmacol. 2011 Jul 1;254(1):8-17. doi: 10.1016/j.taap.2011.03.027. Epub 2011 Apr 12. Toxicol Appl Pharmacol. 2011. PMID: 21504755
Ophiobolin A, a sesterterpenoid fungal phytotoxin, displays higher in vitro growth-inhibitory effects in mammalian than in plant cells and displays in vivo antitumor activity.
Bury M, Novo-Uzal E, Andolfi A, Cimini S, Wauthoz N, Heffeter P, Lallemand B, Avolio F, Delporte C, Cimmino A, Dubois J, Van Antwerpen P, Zonno MC, Vurro M, Poumay Y, Berger W, Evidente A, De Gara L, Kiss R, Locato V. Bury M, et al. Among authors: andolfi a. Int J Oncol. 2013 Aug;43(2):575-85. doi: 10.3892/ijo.2013.1979. Epub 2013 Jun 10. Int J Oncol. 2013. PMID: 23754298
Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
Lamoral-Theys D, Andolfi A, Van Goietsenoven G, Cimmino A, Le Calvé B, Wauthoz N, Mégalizzi V, Gras T, Bruyère C, Dubois J, Mathieu V, Kornienko A, Kiss R, Evidente A. Lamoral-Theys D, et al. Among authors: andolfi a. J Med Chem. 2009 Oct 22;52(20):6244-56. doi: 10.1021/jm901031h. J Med Chem. 2009. PMID: 19788245 Free PMC article.
Fungal metabolites with anticancer activity.
Evidente A, Kornienko A, Cimmino A, Andolfi A, Lefranc F, Mathieu V, Kiss R. Evidente A, et al. Among authors: andolfi a. Nat Prod Rep. 2014 May;31(5):617-27. doi: 10.1039/c3np70078j. Epub 2014 Mar 20. Nat Prod Rep. 2014. PMID: 24651312 Review.
140 results