Sun Y - Search Results

1

RBX1 (RING box protein 1) E3 ubiquitin ligase is required for genomic integrity by modulating DNA replication licensing proteins.

Jia L, Bickel JS, Wu J, Morgan MA, Li H, Yang J, Yu X, Chan RC, Sun Y. Jia L, et al. Among authors: sun y. J Biol Chem. 2011 Feb 4;286(5):3379-86. doi: 10.1074/jbc.M110.188425. Epub 2010 Nov 29. J Biol Chem. 2011. PMID: 21115485 Free PMC article.

2

Targeting E3 ubiquitin ligases for cancer therapy.

Sun Y. Sun Y. Cancer Biol Ther. 2003 Nov-Dec;2(6):623-9. Cancer Biol Ther. 2003. PMID: 14688465 Review.

3

Overview of approaches for screening for ubiquitin ligase inhibitors.

Sun Y. Sun Y. Methods Enzymol. 2005;399:654-63. doi: 10.1016/S0076-6879(05)99043-5. Methods Enzymol. 2005. PMID: 16338387 Review.

4

E3 ubiquitin ligases as cancer targets and biomarkers.

Sun Y. Sun Y. Neoplasia. 2006 Aug;8(8):645-54. doi: 10.1593/neo.06376. Neoplasia. 2006. PMID: 16925947 Free PMC article. Review.

5

SAG/ROC-SCF beta-TrCP E3 ubiquitin ligase promotes pro-caspase-3 degradation as a mechanism of apoptosis protection.

Tan M, Gallegos JR, Gu Q, Huang Y, Li J, Jin Y, Lu H, Sun Y. Tan M, et al. Among authors: sun y. Neoplasia. 2006 Dec;8(12):1042-54. doi: 10.1593/neo.06568. Neoplasia. 2006. PMID: 17217622 Free PMC article.

6

SAG/ROC2 E3 ligase regulates skin carcinogenesis by stage-dependent targeting of c-Jun/AP1 and IkappaB-alpha/NF-kappaB.

Gu Q, Bowden GT, Normolle D, Sun Y. Gu Q, et al. Among authors: sun y. J Cell Biol. 2007 Sep 10;178(6):1009-23. doi: 10.1083/jcb.200612067. J Cell Biol. 2007. PMID: 17846172 Free PMC article.

7

SCF TrCP1 activates and ubiquitylates TAp63gamma.

Gallegos JR, Litersky J, Lee H, Sun Y, Nakayama K, Nakayama K, Lu H. Gallegos JR, et al. Among authors: sun y. J Biol Chem. 2008 Jan 4;283(1):66-75. doi: 10.1074/jbc.M704686200. Epub 2007 Oct 28. J Biol Chem. 2008. PMID: 17965458 Free article.

8

Growth inhibition and radiosensitization of glioblastoma and lung cancer cells by small interfering RNA silencing of tumor necrosis factor receptor-associated factor 2.

Zheng M, Morgan-Lappe SE, Yang J, Bockbrader KM, Pamarthy D, Thomas D, Fesik SW, Sun Y. Zheng M, et al. Among authors: sun y. Cancer Res. 2008 Sep 15;68(18):7570-8. doi: 10.1158/0008-5472.CAN-08-0632. Cancer Res. 2008. PMID: 18794145 Free PMC article.

9

RBX1/ROC1 disruption results in early embryonic lethality due to proliferation failure, partially rescued by simultaneous loss of p27.

Tan M, Davis SW, Saunders TL, Zhu Y, Sun Y. Tan M, et al. Among authors: sun y. Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6203-8. doi: 10.1073/pnas.0812425106. Epub 2009 Mar 26. Proc Natl Acad Sci U S A. 2009. PMID: 19325126 Free PMC article.

10

ROC1/RBX1 E3 ubiquitin ligase silencing suppresses tumor cell growth via sequential induction of G2-M arrest, apoptosis, and senescence.

Jia L, Soengas MS, Sun Y. Jia L, et al. Among authors: sun y. Cancer Res. 2009 Jun 15;69(12):4974-82. doi: 10.1158/0008-5472.CAN-08-4671. Epub 2009 Jun 9. Cancer Res. 2009. PMID: 19509229 Free PMC article.

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