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Page 1
BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha.
Lisbona F, Rojas-Rivera D, Thielen P, Zamorano S, Todd D, Martinon F, Glavic A, Kress C, Lin JH, Walter P, Reed JC, Glimcher LH, Hetz C. Lisbona F, et al. Mol Cell. 2009 Mar 27;33(6):679-91. doi: 10.1016/j.molcel.2009.02.017. Mol Cell. 2009. PMID: 19328063 Free PMC article.
BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α.
Rodriguez DA, Zamorano S, Lisbona F, Rojas-Rivera D, Urra H, Cubillos-Ruiz JR, Armisen R, Henriquez DR, Cheng EH, Letek M, Vaisar T, Irrazabal T, Gonzalez-Billault C, Letai A, Pimentel-Muiños FX, Kroemer G, Hetz C. Rodriguez DA, et al. EMBO J. 2012 May 16;31(10):2322-35. doi: 10.1038/emboj.2012.84. Epub 2012 Apr 17. EMBO J. 2012. PMID: 22510886 Free PMC article.
A BAX/BAK and cyclophilin D-independent intrinsic apoptosis pathway.
Zamorano S, Rojas-Rivera D, Lisbona F, Parra V, Court FA, Villegas R, Cheng EH, Korsmeyer SJ, Lavandero S, Hetz C. Zamorano S, et al. PLoS One. 2012;7(6):e37782. doi: 10.1371/journal.pone.0037782. Epub 2012 Jun 12. PLoS One. 2012. PMID: 22719850 Free PMC article.
Bax Inhibitor-1-mediated Ca2+ leak is decreased by cytosolic acidosis.
Kiviluoto S, Luyten T, Schneider L, Lisak D, Rojas-Rivera D, Welkenhuyzen K, Missaen L, De Smedt H, Parys JB, Hetz C, Methner A, Bultynck G. Kiviluoto S, et al. Cell Calcium. 2013 Sep;54(3):186-92. doi: 10.1016/j.ceca.2013.06.002. Epub 2013 Jul 16. Cell Calcium. 2013. PMID: 23867001
When ER stress reaches a dead end.
Urra H, Dufey E, Lisbona F, Rojas-Rivera D, Hetz C. Urra H, et al. Biochim Biophys Acta. 2013 Dec;1833(12):3507-3517. doi: 10.1016/j.bbamcr.2013.07.024. Epub 2013 Aug 27. Biochim Biophys Acta. 2013. PMID: 23988738 Free article. Review.
Interplay between the oxidoreductase PDIA6 and microRNA-322 controls the response to disrupted endoplasmic reticulum calcium homeostasis.
Groenendyk J, Peng Z, Dudek E, Fan X, Mizianty MJ, Dufey E, Urra H, Sepulveda D, Rojas-Rivera D, Lim Y, Kim DH, Baretta K, Srikanth S, Gwack Y, Ahnn J, Kaufman RJ, Lee SK, Hetz C, Kurgan L, Michalak M. Groenendyk J, et al. Sci Signal. 2014 Jun 10;7(329):ra54. doi: 10.1126/scisignal.2004983. Sci Signal. 2014. PMID: 24917591 Free PMC article.
30 results