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Discovery of novel N-β-D-xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes.
Yao CH, Song JS, Chen CT, Yeh TK, Hung MS, Chang CC, Liu YW, Yuan MC, Hsieh CJ, Huang CY, Wang MH, Chiu CH, Hsieh TC, Wu SH, Hsiao WC, Chu KF, Tsai CH, Chao YS, Lee JC. Yao CH, et al. Among authors: chang cc. J Med Chem. 2011 Jan 13;54(1):166-78. doi: 10.1021/jm101072y. Epub 2010 Dec 3. J Med Chem. 2011. PMID: 21128592
A highly selective and potent CXCR4 antagonist for hepatocellular carcinoma treatment.
Song JS, Chang CC, Wu CH, Dinh TK, Jan JJ, Huang KW, Chou MC, Shiue TY, Yeh KC, Ke YY, Yeh TK, Ta YN, Lee CJ, Huang JK, Sung YC, Shia KS, Chen Y. Song JS, et al. Among authors: chang cc. Proc Natl Acad Sci U S A. 2021 Mar 30;118(13):e2015433118. doi: 10.1073/pnas.2015433118. Proc Natl Acad Sci U S A. 2021. PMID: 33753481 Free PMC article.
Highly efficient and tumor-selective nanoparticles for dual-targeted immunogene therapy against cancer.
Huang KW, Hsu FF, Qiu JT, Chern GJ, Lee YA, Chang CC, Huang YT, Sung YC, Chiang CC, Huang RL, Lin CC, Dinh TK, Huang HC, Shih YC, Alson D, Lin CY, Lin YC, Chang PC, Lin SY, Chen Y. Huang KW, et al. Among authors: chang pc, chang cc. Sci Adv. 2020 Jan 15;6(3):eaax5032. doi: 10.1126/sciadv.aax5032. eCollection 2020 Jan. Sci Adv. 2020. PMID: 31998834 Free PMC article.
Delivery of nitric oxide with a nanocarrier promotes tumour vessel normalization and potentiates anti-cancer therapies.
Sung YC, Jin PR, Chu LA, Hsu FF, Wang MR, Chang CC, Chiou SJ, Qiu JT, Gao DY, Lin CC, Chen YS, Hsu YC, Wang J, Wang FN, Yu PL, Chiang AS, Wu AY, Ko JJ, Lai CP, Lu TT, Chen Y. Sung YC, et al. Among authors: chang cc. Nat Nanotechnol. 2019 Dec;14(12):1160-1169. doi: 10.1038/s41565-019-0570-3. Epub 2019 Nov 18. Nat Nanotechnol. 2019. PMID: 31740794
5,535 results