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Deletion of CDKAL1 affects mitochondrial ATP generation and first-phase insulin exocytosis.
Ohara-Imaizumi M, Yoshida M, Aoyagi K, Saito T, Okamura T, Takenaka H, Akimoto Y, Nakamichi Y, Takanashi-Yanobu R, Nishiwaki C, Kawakami H, Kato N, Hisanaga S, Kakei M, Nagamatsu S. Ohara-Imaizumi M, et al. Among authors: okamura t. PLoS One. 2010 Dec 9;5(12):e15553. doi: 10.1371/journal.pone.0015553. PLoS One. 2010. PMID: 21151568 Free PMC article.
Deletion of CDKAL1 affects high-fat diet-induced fat accumulation and glucose-stimulated insulin secretion in mice, indicating relevance to diabetes.
Okamura T, Yanobu-Takanashi R, Takeuchi F, Isono M, Akiyama K, Shimizu Y, Goto M, Liang YQ, Yamamoto K, Katsuya T, Fujioka A, Ohnaka K, Takayanagi R, Ogihara T, Yamori Y, Kato N. Okamura T, et al. PLoS One. 2012;7(11):e49055. doi: 10.1371/journal.pone.0049055. Epub 2012 Nov 16. PLoS One. 2012. PMID: 23173044 Free PMC article.
Serotonin regulates glucose-stimulated insulin secretion from pancreatic β cells during pregnancy.
Ohara-Imaizumi M, Kim H, Yoshida M, Fujiwara T, Aoyagi K, Toyofuku Y, Nakamichi Y, Nishiwaki C, Okamura T, Uchida T, Fujitani Y, Akagawa K, Kakei M, Watada H, German MS, Nagamatsu S. Ohara-Imaizumi M, et al. Among authors: okamura t. Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19420-5. doi: 10.1073/pnas.1310953110. Epub 2013 Nov 11. Proc Natl Acad Sci U S A. 2013. PMID: 24218571 Free PMC article.
The histidine transporter SLC15A4 coordinates mTOR-dependent inflammatory responses and pathogenic antibody production.
Kobayashi T, Shimabukuro-Demoto S, Yoshida-Sugitani R, Furuyama-Tanaka K, Karyu H, Sugiura Y, Shimizu Y, Hosaka T, Goto M, Kato N, Okamura T, Suematsu M, Yokoyama S, Toyama-Sorimachi N. Kobayashi T, et al. Among authors: okamura t. Immunity. 2014 Sep 18;41(3):375-388. doi: 10.1016/j.immuni.2014.08.011. Immunity. 2014. PMID: 25238095 Free article.
2,907 results