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HER2-positive breast cancer cells resistant to trastuzumab and lapatinib lose reliance upon HER2 and are sensitive to the multitargeted kinase inhibitor sorafenib.
Valabrega G, Capellero S, Cavalloni G, Zaccarello G, Petrelli A, Migliardi G, Milani A, Peraldo-Neia C, Gammaitoni L, Sapino A, Pecchioni C, Moggio A, Giordano S, Aglietta M, Montemurro F. Valabrega G, et al. Among authors: petrelli a. Breast Cancer Res Treat. 2011 Nov;130(1):29-40. doi: 10.1007/s10549-010-1281-5. Epub 2010 Dec 9. Breast Cancer Res Treat. 2011. PMID: 21153051
TGFalpha expression impairs Trastuzumab-induced HER2 downregulation.
Valabrega G, Montemurro F, Sarotto I, Petrelli A, Rubini P, Tacchetti C, Aglietta M, Comoglio PM, Giordano S. Valabrega G, et al. Among authors: petrelli a. Oncogene. 2005 Apr 21;24(18):3002-10. doi: 10.1038/sj.onc.1208478. Oncogene. 2005. PMID: 15735715
MicroRNAs impair MET-mediated invasive growth.
Migliore C, Petrelli A, Ghiso E, Corso S, Capparuccia L, Eramo A, Comoglio PM, Giordano S. Migliore C, et al. Among authors: petrelli a. Cancer Res. 2008 Dec 15;68(24):10128-36. doi: 10.1158/0008-5472.CAN-08-2148. Cancer Res. 2008. PMID: 19074879
Sequential analysis of multistage hepatocarcinogenesis reveals that miR-100 and PLK1 dysregulation is an early event maintained along tumor progression.
Petrelli A, Perra A, Schernhuber K, Cargnelutti M, Salvi A, Migliore C, Ghiso E, Benetti A, Barlati S, Ledda-Columbano GM, Portolani N, De Petro G, Columbano A, Giordano S. Petrelli A, et al. Oncogene. 2012 Oct 18;31(42):4517-26. doi: 10.1038/onc.2011.631. Epub 2012 Jan 16. Oncogene. 2012. PMID: 22249248 Free article.
MicroRNA/gene profiling unveils early molecular changes and nuclear factor erythroid related factor 2 (NRF2) activation in a rat model recapitulating human hepatocellular carcinoma (HCC).
Petrelli A, Perra A, Cora D, Sulas P, Menegon S, Manca C, Migliore C, Kowalik MA, Ledda-Columbano GM, Giordano S, Columbano A. Petrelli A, et al. Hepatology. 2014 Jan;59(1):228-41. doi: 10.1002/hep.26616. Epub 2013 Nov 18. Hepatology. 2014. PMID: 23857252 Free article.
196 results