Hopkins NE - Search Results

1

Inhibition of the binding of 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene to DNA in mouse skin epidermis by 1-ethynylpyrene.

Viaje A, Lu JY, Hopkins NE, Nettikumara AN, DiGiovanni J, Alworth WL, Slaga TJ. Viaje A, et al. Among authors: hopkins ne. Carcinogenesis. 1990 Jul;11(7):1139-43. doi: 10.1093/carcin/11.7.1139. Carcinogenesis. 1990. PMID: 2115405

2

Effects of 1-ethynylpyrene and related inhibitors of P450 isozymes upon benzo[a]pyrene metabolism by liver microsomes.

Hall M, Parker DK, Grover PL, Lu JY, Hopkins NE, Alworth WL. Hall M, et al. Among authors: hopkins ne. Chem Biol Interact. 1990;76(2):181-92. doi: 10.1016/0009-2797(90)90087-4. Chem Biol Interact. 1990. PMID: 2225228

3

Suicide inhibitors of cytochrome P450 1A1 and P450 2B1.

Hopkins NE, Foroozesh MK, Alworth WL. Hopkins NE, et al. Biochem Pharmacol. 1992 Aug 18;44(4):787-96. doi: 10.1016/0006-2952(92)90417-h. Biochem Pharmacol. 1992. PMID: 1510726

4

2-ethynylnaphthalene as a mechanism-based inactivator of the cytochrome P-450 catalyzed N-oxidation of 2-naphthylamine.

Hammons GJ, Alworth WL, Hopkins NE, Guengerich FP, Kadlubar FF. Hammons GJ, et al. Among authors: hopkins ne. Chem Res Toxicol. 1989 Nov-Dec;2(6):367-74. doi: 10.1021/tx00012a003. Chem Res Toxicol. 1989. PMID: 2519725

5

Mechanism-based inactivation of cytochrome P450 2B1 by 2-ethynylnaphthalene: identification of an active-site peptide.

Roberts ES, Hopkins NE, Alworth WL, Hollenberg PF. Roberts ES, et al. Among authors: hopkins ne. Chem Res Toxicol. 1993 Jul-Aug;6(4):470-9. doi: 10.1021/tx00034a013. Chem Res Toxicol. 1993. PMID: 8374044

6

Selectivity of polycyclic inhibitors for human cytochrome P450s 1A1, 1A2, and 1B1.

Shimada T, Yamazaki H, Foroozesh M, Hopkins NE, Alworth WL, Guengerich FP. Shimada T, et al. Among authors: hopkins ne. Chem Res Toxicol. 1998 Sep;11(9):1048-56. doi: 10.1021/tx980090+. Chem Res Toxicol. 1998. PMID: 9760279

7

Modification of cytochrome P450 1A2 enzymes by the mechanism-based inactivator 2-ethynylnaphthalene and the photoaffinity label 4-azidobiphenyl.

Yun CH, Hammons GJ, Jones G, Martin MV, Hopkins NE, Alworth WL, Guengerich FP. Yun CH, et al. Among authors: hopkins ne. Biochemistry. 1992 Nov 3;31(43):10556-63. doi: 10.1021/bi00158a019. Biochemistry. 1992. PMID: 1420171

8

Induction of CYP102 (cytochrome P450BM-3) in Bacillus megaterium by 17 beta-estradiol and 4-sec-butylphenol.

Hopkins NE, English N, Hughes V, Rowley CW, Wolf CR, Alworth WL. Hopkins NE, et al. Biochem Biophys Res Commun. 1998 Mar 27;244(3):868-72. doi: 10.1006/bbrc.1998.8170. Biochem Biophys Res Commun. 1998. PMID: 9535758

9

Inactivation of cytochrome P450s 2B1, 2B4, 2B6, and 2B11 by arylalkynes.

Roberts ES, Hopkins NE, Foroozesh M, Alworth WL, Halpert JR, Hollenberg PF. Roberts ES, et al. Among authors: hopkins ne. Drug Metab Dispos. 1997 Nov;25(11):1242-8. Drug Metab Dispos. 1997. PMID: 9351899 Clinical Trial.

10

Mechanistic studies of 9-ethynylphenanthrene-inactivated cytochrome P450 2B1.

Roberts ES, Ballou DP, Hopkins NE, Alworth WL, Hollenberg PF. Roberts ES, et al. Among authors: hopkins ne. Arch Biochem Biophys. 1995 Nov 10;323(2):303-12. doi: 10.1006/abbi.1995.9960. Arch Biochem Biophys. 1995. PMID: 7487092

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