García-Higuera I - Search Results

1

Targeting mitotic exit leads to tumor regression in vivo: Modulation by Cdk1, Mastl, and the PP2A/B55α,δ phosphatase.

Manchado E, Guillamot M, de Cárcer G, Eguren M, Trickey M, García-Higuera I, Moreno S, Yamano H, Cañamero M, Malumbres M. Manchado E, et al. Cancer Cell. 2010 Dec 14;18(6):641-54. doi: 10.1016/j.ccr.2010.10.028. Cancer Cell. 2010. PMID: 21156286 Free article.

2

Genomic stability and tumour suppression by the APC/C cofactor Cdh1.

García-Higuera I, Manchado E, Dubus P, Cañamero M, Méndez J, Moreno S, Malumbres M. García-Higuera I, et al. Nat Cell Biol. 2008 Jul;10(7):802-11. doi: 10.1038/ncb1742. Epub 2008 Jun 15. Nat Cell Biol. 2008. PMID: 18552834

3

The APC/C cofactor Cdh1 prevents replicative stress and p53-dependent cell death in neural progenitors.

Eguren M, Porlan E, Manchado E, García-Higuera I, Cañamero M, Fariñas I, Malumbres M. Eguren M, et al. Among authors: garcia higuera i. Nat Commun. 2013;4:2880. doi: 10.1038/ncomms3880. Nat Commun. 2013. PMID: 24301385 Free article.

4

APC(FZR1) prevents nondisjunction in mouse oocytes by controlling meiotic spindle assembly timing.

Holt JE, Lane SI, Jennings P, García-Higuera I, Moreno S, Jones KT. Holt JE, et al. Among authors: garcia higuera i. Mol Biol Cell. 2012 Oct;23(20):3970-81. doi: 10.1091/mbc.E12-05-0352. Epub 2012 Aug 23. Mol Biol Cell. 2012. PMID: 22918942 Free PMC article.

5

APC/C-Cdh1 coordinates neurogenesis and cortical size during development.

Delgado-Esteban M, García-Higuera I, Maestre C, Moreno S, Almeida A. Delgado-Esteban M, et al. Among authors: garcia higuera i. Nat Commun. 2013;4:2879. doi: 10.1038/ncomms3879. Nat Commun. 2013. PMID: 24301314 Free article.

6

The E3 ubiquitin ligase APC/C-Cdh1 coordinates neurogenesis and cortical size during development.

Delgado-Esteban M, Garcia-Higuera I, Moreno S, Almeida A. Delgado-Esteban M, et al. Among authors: garcia higuera i. Free Radic Biol Med. 2014 Oct;75 Suppl 1:S4-5. doi: 10.1016/j.freeradbiomed.2014.10.834. Epub 2014 Dec 10. Free Radic Biol Med. 2014. PMID: 26461363

7

Efficient terminal erythroid differentiation requires the APC/C cofactor Cdh1 to limit replicative stress in erythroblasts.

Cuadrado M, Garzón J, Moreno S, García-Higuera I. Cuadrado M, et al. Among authors: garcia higuera i. Sci Rep. 2022 Jun 21;12(1):10489. doi: 10.1038/s41598-022-14331-6. Sci Rep. 2022. PMID: 35729193 Free PMC article.

8

Shortage of dNTPs underlies altered replication dynamics and DNA breakage in the absence of the APC/C cofactor Cdh1.

Garzón J, Rodríguez R, Kong Z, Chabes A, Rodríguez-Acebes S, Méndez J, Moreno S, García-Higuera I. Garzón J, et al. Among authors: garcia higuera i. Oncogene. 2017 Oct 19;36(42):5808-5818. doi: 10.1038/onc.2017.186. Epub 2017 Jun 12. Oncogene. 2017. PMID: 28604743

9

The APC activator fizzy-related-1 (FZR1) is needed for preimplantation mouse embryo development.

Seah MK, Holt JE, García-Higuera I, Moreno S, Jones KT. Seah MK, et al. Among authors: garcia higuera i. J Cell Sci. 2012 Dec 15;125(Pt 24):6030-7. doi: 10.1242/jcs.110155. Epub 2012 Oct 24. J Cell Sci. 2012. PMID: 23097041

10

The APC/C activator FZR1 coordinates the timing of meiotic resumption during prophase I arrest in mammalian oocytes.

Holt JE, Tran SM, Stewart JL, Minahan K, García-Higuera I, Moreno S, Jones KT. Holt JE, et al. Development. 2011 Mar;138(5):905-13. doi: 10.1242/dev.059022. Epub 2011 Jan 26. Development. 2011. PMID: 21270054

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