Gao LJ - Search Results

1

Discovery of 7-N-piperazinylthiazolo[5,4-d]pyrimidine analogues as a novel class of immunosuppressive agents with in vivo biological activity.

Jang MY, Lin Y, De Jonghe S, Gao LJ, Vanderhoydonck B, Froeyen M, Rozenski J, Herman J, Louat T, Van Belle K, Waer M, Herdewijn P. Jang MY, et al. Among authors: gao lj. J Med Chem. 2011 Jan 27;54(2):655-68. doi: 10.1021/jm101254z. Epub 2010 Dec 20. J Med Chem. 2011. PMID: 21171614

2

Anti-inflammatory activity of a pteridine derivative (4AZA2096) alleviates TNBS-induced colitis in mice.

Shen C, Dillissen E, Kasran A, Lin Y, Clydesdale G, Sienaert I, Jonghe SD, Gao LJ, Geboes K, Boon L, Rutgeerts P, Ceuppens JL. Shen C, et al. Among authors: gao lj. J Interferon Cytokine Res. 2006 Aug;26(8):575-82. doi: 10.1089/jir.2006.26.575. J Interferon Cytokine Res. 2006. PMID: 16881868

3

Isolation and purification of a new kalimantacin/batumin-related polyketide antibiotic and elucidation of its biosynthesis gene cluster.

Mattheus W, Gao LJ, Herdewijn P, Landuyt B, Verhaegen J, Masschelein J, Volckaert G, Lavigne R. Mattheus W, et al. Among authors: gao lj. Chem Biol. 2010 Feb 26;17(2):149-59. doi: 10.1016/j.chembiol.2010.01.014. Chem Biol. 2010. PMID: 20189105

4

The kalimantacin/batumin biosynthesis operon encodes a self-resistance isoform of the FabI bacterial target.

Mattheus W, Masschelein J, Gao LJ, Herdewijn P, Landuyt B, Volckaert G, Lavigne R. Mattheus W, et al. Among authors: gao lj. Chem Biol. 2010 Oct 29;17(10):1067-71. doi: 10.1016/j.chembiol.2010.07.015. Chem Biol. 2010. PMID: 21035728

5

Synthesis and in vitro evaluation of 2-amino-4-N-piperazinyl-6-(3,4-dimethoxyphenyl)-pteridines as dual immunosuppressive and anti-inflammatory agents.

De Jonghe S, Marchand A, Gao LJ, Calleja A, Cuveliers E, Sienaert I, Herman J, Clydesdale G, Sefrioui H, Lin Y, Pfleiderer W, Waer M, Herdewijn P. De Jonghe S, et al. Among authors: gao lj. Bioorg Med Chem Lett. 2011 Jan 1;21(1):145-9. doi: 10.1016/j.bmcl.2010.11.053. Epub 2010 Nov 16. Bioorg Med Chem Lett. 2011. PMID: 21131199 Free article.

6

Synthesis and evaluation of novel ligands for the histamine H₄ receptor based on a pyrrolo[2,3-d]pyrimidine scaffold.

Gao LJ, Schwed JS, Weizel L, De Jonghe S, Stark H, Herdewijn P. Gao LJ, et al. Bioorg Med Chem Lett. 2013 Jan 1;23(1):132-7. doi: 10.1016/j.bmcl.2012.10.139. Epub 2012 Nov 15. Bioorg Med Chem Lett. 2013. PMID: 23218604

7

A PKS/NRPS/FAS hybrid gene cluster from Serratia plymuthica RVH1 encoding the biosynthesis of three broad spectrum, zeamine-related antibiotics.

Masschelein J, Mattheus W, Gao LJ, Moons P, Van Houdt R, Uytterhoeven B, Lamberigts C, Lescrinier E, Rozenski J, Herdewijn P, Aertsen A, Michiels C, Lavigne R. Masschelein J, et al. Among authors: gao lj. PLoS One. 2013;8(1):e54143. doi: 10.1371/journal.pone.0054143. Epub 2013 Jan 17. PLoS One. 2013. PMID: 23349809 Free PMC article.

8

Synthesis and structure-activity relationship studies of 2-(1,3,4-oxadiazole-2(3H)-thione)-3-amino-5-arylthieno[2,3-b]pyridines as inhibitors of DRAK2.

Leonczak P, Gao LJ, Ramadori AT, Lescrinier E, Rozenski J, De Jonghe S, Herdewijn P. Leonczak P, et al. Among authors: gao lj. ChemMedChem. 2014 Nov;9(11):2587-601. doi: 10.1002/cmdc.201402234. Epub 2014 Aug 21. ChemMedChem. 2014. PMID: 25146684

9

Discovery of dual death-associated protein related apoptosis inducing protein kinase 1 and 2 inhibitors by a scaffold hopping approach.

Gao LJ, Kovackova S, Sála M, Ramadori AT, De Jonghe S, Herdewijn P. Gao LJ, et al. J Med Chem. 2014 Sep 25;57(18):7624-43. doi: 10.1021/jm5007929. Epub 2014 Sep 11. J Med Chem. 2014. PMID: 25178155

10

L-Aspartic and l-glutamic acid ester-based ProTides of anticancer nucleosides: Synthesis and antitumoral evaluation.

Gao LJ, De Jonghe S, Daelemans D, Herdewijn P. Gao LJ, et al. Bioorg Med Chem Lett. 2016 May 1;26(9):2142-6. doi: 10.1016/j.bmcl.2016.03.076. Epub 2016 Mar 22. Bioorg Med Chem Lett. 2016. PMID: 27032331

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