Herdewijn P - Search Results

1

Discovery of 7-N-piperazinylthiazolo[5,4-d]pyrimidine analogues as a novel class of immunosuppressive agents with in vivo biological activity.

Jang MY, Lin Y, De Jonghe S, Gao LJ, Vanderhoydonck B, Froeyen M, Rozenski J, Herman J, Louat T, Van Belle K, Waer M, Herdewijn P. Jang MY, et al. Among authors: herdewijn p. J Med Chem. 2011 Jan 27;54(2):655-68. doi: 10.1021/jm101254z. Epub 2010 Dec 20. J Med Chem. 2011. PMID: 21171614

2

Synthesis and antiviral activity of acyclic nucleosides with a 3(S),5-dihydroxypentyl or 4(R)-methoxy-3(S),5-dihydroxypentyl side chain.

Vandendriessche F, Snoeck R, Janssen G, Hoogmartens J, Van Aerschot A, De Clercq E, Herdewijn P. Vandendriessche F, et al. Among authors: herdewijn p. J Med Chem. 1992 Apr 17;35(8):1458-65. doi: 10.1021/jm00086a015. J Med Chem. 1992. PMID: 1315394

3

5-(5-Bromothien-2-yl)-2'-deoxyuridine and 5-(5-chlorothien-2-yl)-2'-deoxyuridine are equipotent to (E)-5-(2-bromovinyl)-2'-deoxyuridine in the inhibition of herpes simplex virus type I replication.

Wigerinck P, Pannecouque C, Snoeck R, Claes P, De Clercq E, Herdewijn P. Wigerinck P, et al. Among authors: herdewijn p. J Med Chem. 1991 Aug;34(8):2383-9. doi: 10.1021/jm00112a011. J Med Chem. 1991. PMID: 1652017

4

5'-O-phosphonomethyl-2',3'-dideoxynucleosides: synthesis and anti-HIV activity.

Jie L, Van Aerschot A, Balzarini J, Janssen G, Busson R, Hoogmartens J, De Clercq E, Herdewijn P. Jie L, et al. Among authors: herdewijn p. J Med Chem. 1990 Sep;33(9):2481-7. doi: 10.1021/jm00171a023. J Med Chem. 1990. PMID: 1697345

5

Synthesis and antiviral activity of 5-heteroaryl-substituted 2'-deoxyuridines.

Wigerinck P, Snoeck R, Claes P, De Clercq E, Herdewijn P. Wigerinck P, et al. Among authors: herdewijn p. J Med Chem. 1991 Jun;34(6):1767-72. doi: 10.1021/jm00110a003. J Med Chem. 1991. PMID: 2061920

6

Synthesis and antiviral activity of 3'-heterocyclic substituted 3'-deoxythymidines.

Wigerinck P, Van Aerschot A, Janssen G, Claes P, Balzarini J, De Clercq E, Herdewijn P. Wigerinck P, et al. Among authors: herdewijn p. J Med Chem. 1990 Feb;33(2):868-73. doi: 10.1021/jm00164a063. J Med Chem. 1990. PMID: 2299650

7

3'-Fluoro-2',3'-dideoxy-5-chlorouridine: most selective anti-HIV-1 agent among a series of new 2'- and 3'-fluorinated 2',3'-dideoxynucleoside analogues.

Van Aerschot A, Herdewijn P, Balzarini J, Pauwels R, De Clercq E. Van Aerschot A, et al. Among authors: herdewijn p. J Med Chem. 1989 Aug;32(8):1743-9. doi: 10.1021/jm00128a013. J Med Chem. 1989. PMID: 2754700

8

Synthesis and anti-HIV activity of different sugar-modified pyrimidine and purine nucleosides.

Herdewijn P, Balzarini J, Baba M, Pauwels R, Van Aerschot A, Janssen G, De Clercq E. Herdewijn P, et al. J Med Chem. 1988 Oct;31(10):2040-8. doi: 10.1021/jm00118a033. J Med Chem. 1988. PMID: 3172142

9

Synthesis and anti-HIV activity of various 2'- and 3'-substituted 2',3'-dideoxyadenosines: a structure-activity analysis.

Herdewijn P, Pauwels R, Baba M, Balzarini J, De Clercq E. Herdewijn P, et al. J Med Chem. 1987 Nov;30(11):2131-7. doi: 10.1021/jm00394a034. J Med Chem. 1987. PMID: 3499515

10

An acyclic 5-nitroindazole nucleoside analogue as ambiguous nucleoside.

Van Aerschot A, Rozenski J, Loakes D, Pillet N, Schepers G, Herdewijn P. Van Aerschot A, et al. Among authors: herdewijn p. Nucleic Acids Res. 1995 Nov 11;23(21):4363-70. doi: 10.1093/nar/23.21.4363. Nucleic Acids Res. 1995. PMID: 7501457 Free PMC article.

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