Waer M - Search Results

1

Discovery of 7-N-piperazinylthiazolo[5,4-d]pyrimidine analogues as a novel class of immunosuppressive agents with in vivo biological activity.

Jang MY, Lin Y, De Jonghe S, Gao LJ, Vanderhoydonck B, Froeyen M, Rozenski J, Herman J, Louat T, Van Belle K, Waer M, Herdewijn P. Jang MY, et al. Among authors: waer m. J Med Chem. 2011 Jan 27;54(2):655-68. doi: 10.1021/jm101254z. Epub 2010 Dec 20. J Med Chem. 2011. PMID: 21171614

2

Pathogenesis of autoimmunity after xenogeneic thymus transplantation.

Yan Y, Devos T, Yu L, Xia G, Rutgeerts O, Goebels J, Segers C, Lin Y, Vandeputte M, Waer M. Yan Y, et al. Among authors: waer m. J Immunol. 2003 Jun 15;170(12):5936-46. doi: 10.4049/jimmunol.170.12.5936. J Immunol. 2003. PMID: 12794120

3

Effects of a short course of leflunomide on T-independent B-lymphocyte xenoreactivity and on susceptibility of xenografts to acute or chronic rejection.

Yan Y, Verbeken E, Yu L, Rutgeerts O, Goebels J, Segers C, Lin Y, Waer M. Yan Y, et al. Among authors: waer m. Transplantation. 2005 Jan 27;79(2):135-41; discussion 133-4. doi: 10.1097/01.tp.0000147464.63188.4b. Transplantation. 2005. PMID: 15665760

4

Induction and maintenance of T-dependent or T-independent xenotolerance by nonprimarily-vascularized skin or thymus grafts.

Yu L, Yan Y, Li S, Rutgeerts O, Goebels J, Segers C, Lin Y, Vandeputte M, Waer M. Yu L, et al. Among authors: waer m. Transplantation. 2005 Mar 15;79(5):520-7. doi: 10.1097/01.tp.0000145522.26428.27. Transplantation. 2005. PMID: 15753840

5

Occurrence of autoimmunity after xenothymus transplantation in T-cell-deficient mice depends on the thymus transplant technique.

Devos T, Sprangers B, Lin Y, Li S, Yan Y, Landuyt W, Lenaerts C, Rutgeerts O, Goebels J, Bullens D, De Wolf-Peeters C, Mathieu C, Waer M, Billiau AD. Devos T, et al. Among authors: waer m. Transplantation. 2008 Feb 27;85(4):640-4. doi: 10.1097/TP.0b013e3181613f0c. Transplantation. 2008. PMID: 18347545

6

Aminoacyl-tRNA synthetase inhibitors as potent and synergistic immunosuppressants.

Van de Vijver P, Ostrowski T, Sproat B, Goebels J, Rutgeerts O, Van Aerschot A, Waer M, Herdewijn P. Van de Vijver P, et al. Among authors: waer m. J Med Chem. 2008 May 22;51(10):3020-9. doi: 10.1021/jm8000746. Epub 2008 Apr 26. J Med Chem. 2008. PMID: 18438987

7

Synthesis, immunosuppressive activity and structure-activity relationship study of a new series of 4-N-piperazinyl-thieno[2,3-d]pyrimidine analogues.

Jang MY, De Jonghe S, Van Belle K, Louat T, Waer M, Herdewijn P. Jang MY, et al. Among authors: waer m. Bioorg Med Chem Lett. 2010 Feb 1;20(3):844-7. doi: 10.1016/j.bmcl.2009.12.098. Epub 2010 Jan 4. Bioorg Med Chem Lett. 2010. PMID: 20064721

8

Synthesis and in vitro evaluation of 2-amino-4-N-piperazinyl-6-(3,4-dimethoxyphenyl)-pteridines as dual immunosuppressive and anti-inflammatory agents.

De Jonghe S, Marchand A, Gao LJ, Calleja A, Cuveliers E, Sienaert I, Herman J, Clydesdale G, Sefrioui H, Lin Y, Pfleiderer W, Waer M, Herdewijn P. De Jonghe S, et al. Among authors: waer m. Bioorg Med Chem Lett. 2011 Jan 1;21(1):145-9. doi: 10.1016/j.bmcl.2010.11.053. Epub 2010 Nov 16. Bioorg Med Chem Lett. 2011. PMID: 21131199 Free article.

9

Synthesis of a 2,4,6-trisubstituted 5-cyano-pyrimidine library and evaluation of its immunosuppressive activity in a Mixed Lymphocyte Reaction assay.

Stella A, Van Belle K, De Jonghe S, Louat T, Herman J, Rozenski J, Waer M, Herdewijn P. Stella A, et al. Among authors: waer m. Bioorg Med Chem. 2013 Mar 1;21(5):1209-18. doi: 10.1016/j.bmc.2012.12.032. Epub 2013 Jan 4. Bioorg Med Chem. 2013. PMID: 23347804 Free article.

10

γ-Hydroxyethyl piperidine iminosugar and N-alkylated derivatives: a study of their activity as glycosidase inhibitors and as immunosuppressive agents.

Markad PR, Sonawane DP, Ghosh S, Chopade BA, Kumbhar N, Louat T, Herman J, Waer M, Herdewijn P, Dhavale DD. Markad PR, et al. Among authors: waer m. Bioorg Med Chem. 2014 Nov 1;22(21):5776-82. doi: 10.1016/j.bmc.2014.09.034. Epub 2014 Oct 7. Bioorg Med Chem. 2014. PMID: 25305010

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