Crouch RJ - Search Results

1

The structural and biochemical characterization of human RNase H2 complex reveals the molecular basis for substrate recognition and Aicardi-Goutières syndrome defects.

Figiel M, Chon H, Cerritelli SM, Cybulska M, Crouch RJ, Nowotny M. Figiel M, et al. Among authors: crouch rj. J Biol Chem. 2011 Mar 25;286(12):10540-50. doi: 10.1074/jbc.M110.181974. Epub 2010 Dec 22. J Biol Chem. 2011. PMID: 21177858 Free PMC article.

2

Specific recognition of RNA/DNA hybrid and enhancement of human RNase H1 activity by HBD.

Nowotny M, Cerritelli SM, Ghirlando R, Gaidamakov SA, Crouch RJ, Yang W. Nowotny M, et al. Among authors: crouch rj. EMBO J. 2008 Apr 9;27(7):1172-81. doi: 10.1038/emboj.2008.44. Epub 2008 Mar 13. EMBO J. 2008. PMID: 18337749 Free PMC article.

3

Crystal structures of RNase H2 in complex with nucleic acid reveal the mechanism of RNA-DNA junction recognition and cleavage.

Rychlik MP, Chon H, Cerritelli SM, Klimek P, Crouch RJ, Nowotny M. Rychlik MP, et al. Among authors: crouch rj. Mol Cell. 2010 Nov 24;40(4):658-70. doi: 10.1016/j.molcel.2010.11.001. Mol Cell. 2010. PMID: 21095591 Free PMC article.

4

Crystal structures of RNase H bound to an RNA/DNA hybrid: substrate specificity and metal-dependent catalysis.

Nowotny M, Gaidamakov SA, Crouch RJ, Yang W. Nowotny M, et al. Among authors: crouch rj. Cell. 2005 Jul 1;121(7):1005-16. doi: 10.1016/j.cell.2005.04.024. Cell. 2005. PMID: 15989951 Free article.

5

Structure of human RNase H1 complexed with an RNA/DNA hybrid: insight into HIV reverse transcription.

Nowotny M, Gaidamakov SA, Ghirlando R, Cerritelli SM, Crouch RJ, Yang W. Nowotny M, et al. Among authors: crouch rj. Mol Cell. 2007 Oct 26;28(2):264-76. doi: 10.1016/j.molcel.2007.08.015. Mol Cell. 2007. PMID: 17964265 Free article.

6

Contributions of the two accessory subunits, RNASEH2B and RNASEH2C, to the activity and properties of the human RNase H2 complex.

Chon H, Vassilev A, DePamphilis ML, Zhao Y, Zhang J, Burgers PM, Crouch RJ, Cerritelli SM. Chon H, et al. Among authors: crouch rj. Nucleic Acids Res. 2009 Jan;37(1):96-110. doi: 10.1093/nar/gkn913. Epub 2008 Nov 16. Nucleic Acids Res. 2009. PMID: 19015152 Free PMC article.

7

Ribonuclease H: the enzymes in eukaryotes.

Cerritelli SM, Crouch RJ. Cerritelli SM, et al. Among authors: crouch rj. FEBS J. 2009 Mar;276(6):1494-505. doi: 10.1111/j.1742-4658.2009.06908.x. Epub 2008 Feb 18. FEBS J. 2009. PMID: 19228196 Free PMC article. Review.

8

RNase H2 roles in genome integrity revealed by unlinking its activities.

Chon H, Sparks JL, Rychlik M, Nowotny M, Burgers PM, Crouch RJ, Cerritelli SM. Chon H, et al. Among authors: crouch rj. Nucleic Acids Res. 2013 Mar 1;41(5):3130-43. doi: 10.1093/nar/gkt027. Epub 2013 Jan 25. Nucleic Acids Res. 2013. PMID: 23355612 Free PMC article.

9

RNase H2 catalytic core Aicardi-Goutières syndrome-related mutant invokes cGAS-STING innate immune-sensing pathway in mice.

Pokatayev V, Hasin N, Chon H, Cerritelli SM, Sakhuja K, Ward JM, Morris HD, Yan N, Crouch RJ. Pokatayev V, et al. Among authors: crouch rj. J Exp Med. 2016 Mar 7;213(3):329-36. doi: 10.1084/jem.20151464. Epub 2016 Feb 15. J Exp Med. 2016. PMID: 26880576 Free PMC article.

10

RNase H2-RED carpets the path to eukaryotic RNase H2 functions.

Cerritelli SM, Crouch RJ. Cerritelli SM, et al. Among authors: crouch rj. DNA Repair (Amst). 2019 Dec;84:102736. doi: 10.1016/j.dnarep.2019.102736. Epub 2019 Oct 23. DNA Repair (Amst). 2019. PMID: 31761672 Free PMC article. Review.

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