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148 results

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Page 1
The discovery of sulfonylated dipeptides as potent VLA-4 antagonists.
Hagmann WK, Durette PL, Lanza T, Kevin NJ, de Laszlo SE, Kopka IE, Young D, Magriotis PA, Li B, Lin LS, Yang G, Kamenecka T, Chang LL, Wilson J, MacCoss M, Mills SG, Van Riper G, McCauley E, Egger LA, Kidambi U, Lyons K, Vincent S, Stearns R, Colletti A, Teffera J, Tong S, Fenyk-Melody J, Owens K, Levorse D, Kim P, Schmidt JA, Mumford RA. Hagmann WK, et al. Bioorg Med Chem Lett. 2001 Oct 22;11(20):2709-13. doi: 10.1016/s0960-894x(01)00544-3. Bioorg Med Chem Lett. 2001. PMID: 11591507
N-(arylacetyl)-biphenylalanines as potent VLA-4 antagonists.
Li B, de Laszlo SE, Kamenecka TM, Kopka IE, Durette PL, Lanza T Jr, MacCoss M, Tong S, Mumford RA, McCauley ED, Van Riper G, Schmidt JA, Hagmann WK. Li B, et al. Among authors: kamenecka tm. Bioorg Med Chem Lett. 2002 Aug 19;12(16):2141-4. doi: 10.1016/s0960-894x(02)00366-9. Bioorg Med Chem Lett. 2002. PMID: 12127523
5-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-2,3'-bipyridine: a highly potent, orally active metabotropic glutamate subtype 5 (mGlu5) receptor antagonist with anxiolytic activity.
Roppe JR, Wang B, Huang D, Tehrani L, Kamenecka T, Schweiger EJ, Anderson JJ, Brodkin J, Jiang X, Cramer M, Chung J, Reyes-Manalo G, Munoz B, Cosford ND. Roppe JR, et al. Bioorg Med Chem Lett. 2004 Aug 2;14(15):3993-6. doi: 10.1016/j.bmcl.2004.05.037. Bioorg Med Chem Lett. 2004. PMID: 15225713
3,5-Disubstituted quinolines as novel c-Jun N-terminal kinase inhibitors.
Jiang R, Duckett D, Chen W, Habel J, Ling YY, LoGrasso P, Kamenecka TM. Jiang R, et al. Among authors: kamenecka tm. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6378-82. doi: 10.1016/j.bmcl.2007.08.054. Epub 2007 Aug 26. Bioorg Med Chem Lett. 2007. PMID: 17911023
Inhibitors of c-jun-N-terminal kinase (JNK).
LoGrasso P, Kamenecka T. LoGrasso P, et al. Mini Rev Med Chem. 2008 Jul;8(8):755-66. doi: 10.2174/138955708784912120. Mini Rev Med Chem. 2008. PMID: 18673131
Insular hypocretin transmission regulates nicotine reward.
Hollander JA, Lu Q, Cameron MD, Kamenecka TM, Kenny PJ. Hollander JA, et al. Among authors: kamenecka tm. Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19480-5. doi: 10.1073/pnas.0808023105. Epub 2008 Nov 24. Proc Natl Acad Sci U S A. 2008. PMID: 19033203 Free PMC article.
148 results