Ralvenius WT - Search Results

1

A virus-like particle-based anti-nerve growth factor vaccine reduces inflammatory hyperalgesia: potential long-term therapy for chronic pain.

Röhn TA, Ralvenius WT, Paul J, Borter P, Hernandez M, Witschi R, Grest P, Zeilhofer HU, Bachmann MF, Jennings GT. Röhn TA, et al. Among authors: ralvenius wt. J Immunol. 2011 Feb 1;186(3):1769-80. doi: 10.4049/jimmunol.1000030. Epub 2010 Dec 29. J Immunol. 2011. PMID: 21191068

2

Antihyperalgesia by α2-GABAA receptors occurs via a genuine spinal action and does not involve supraspinal sites.

Paul J, Yévenes GE, Benke D, Di Lio A, Ralvenius WT, Witschi R, Scheurer L, Cook JM, Rudolph U, Fritschy JM, Zeilhofer HU. Paul J, et al. Among authors: ralvenius wt. Neuropsychopharmacology. 2014 Jan;39(2):477-87. doi: 10.1038/npp.2013.221. Epub 2013 Aug 28. Neuropsychopharmacology. 2014. PMID: 24045508 Free PMC article.

3

Restoring the spinal pain gate: GABA(A) receptors as targets for novel analgesics.

Zeilhofer HU, Ralvenius WT, Acuña MA. Zeilhofer HU, et al. Among authors: ralvenius wt. Adv Pharmacol. 2015;73:71-96. doi: 10.1016/bs.apha.2014.11.007. Epub 2015 Jan 14. Adv Pharmacol. 2015. PMID: 25637438

4

Acetaminophen Relieves Inflammatory Pain through CB₁ Cannabinoid Receptors in the Rostral Ventromedial Medulla.

Klinger-Gratz PP, Ralvenius WT, Neumann E, Kato A, Nyilas R, Lele Z, Katona I, Zeilhofer HU. Klinger-Gratz PP, et al. Among authors: ralvenius wt. J Neurosci. 2018 Jan 10;38(2):322-334. doi: 10.1523/JNEUROSCI.1945-17.2017. Epub 2017 Nov 22. J Neurosci. 2018. PMID: 29167401 Free PMC article.

5

Analgesia and unwanted benzodiazepine effects in point-mutated mice expressing only one benzodiazepine-sensitive GABAA receptor subtype.

Ralvenius WT, Benke D, Acuña MA, Rudolph U, Zeilhofer HU. Ralvenius WT, et al. Nat Commun. 2015 Apr 13;6:6803. doi: 10.1038/ncomms7803. Nat Commun. 2015. PMID: 25865415 Free PMC article.

6

The clobazam metabolite N-desmethyl clobazam is an α2 preferring benzodiazepine with an improved therapeutic window for antihyperalgesia.

Ralvenius WT, Acuña MA, Benke D, Matthey A, Daali Y, Rudolph U, Desmeules J, Zeilhofer HU, Besson M. Ralvenius WT, et al. Neuropharmacology. 2016 Oct;109:366-375. doi: 10.1016/j.neuropharm.2016.07.004. Epub 2016 Jul 5. Neuropharmacology. 2016. PMID: 27392635 Free PMC article.

7

Targeted ablation, silencing, and activation establish glycinergic dorsal horn neurons as key components of a spinal gate for pain and itch.

Foster E, Wildner H, Tudeau L, Haueter S, Ralvenius WT, Jegen M, Johannssen H, Hösli L, Haenraets K, Ghanem A, Conzelmann KK, Bösl M, Zeilhofer HU. Foster E, et al. Among authors: ralvenius wt. Neuron. 2015 Mar 18;85(6):1289-304. doi: 10.1016/j.neuron.2015.02.028. Neuron. 2015. PMID: 25789756 Free PMC article.

8

Phosphorylation state-dependent modulation of spinal glycine receptors alleviates inflammatory pain.

Acuña MA, Yévenes GE, Ralvenius WT, Benke D, Di Lio A, Lara CO, Muñoz B, Burgos CF, Moraga-Cid G, Corringer PJ, Zeilhofer HU. Acuña MA, et al. Among authors: ralvenius wt. J Clin Invest. 2016 Jul 1;126(7):2547-60. doi: 10.1172/JCI83817. Epub 2016 Jun 6. J Clin Invest. 2016. PMID: 27270175 Free PMC article.

9

TP003 is a non-selective benzodiazepine site agonist that induces anxiolysis via α2GABA_A receptors.

Neumann E, Ralvenius WT, Acuña MA, Rudolph U, Zeilhofer HU. Neumann E, et al. Among authors: ralvenius wt. Neuropharmacology. 2018 Dec;143:71-78. doi: 10.1016/j.neuropharm.2018.09.026. Epub 2018 Sep 18. Neuropharmacology. 2018. PMID: 30240781

10

Localization and production of peptide endocannabinoids in the rodent CNS and adrenal medulla.

Hofer SC, Ralvenius WT, Gachet MS, Fritschy JM, Zeilhofer HU, Gertsch J. Hofer SC, et al. Among authors: ralvenius wt. Neuropharmacology. 2015 Nov;98:78-89. doi: 10.1016/j.neuropharm.2015.03.021. Epub 2015 Mar 31. Neuropharmacology. 2015. PMID: 25839900

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