Begley TJ - Search Results

1

Cross-species Functionome analysis identifies proteins associated with DNA repair, translation and aerobic respiration as conserved modulators of UV-toxicity.

Rooney JP, Patil A, Joseph F, Endres L, Begley U, Zappala MR, Cunningham RP, Begley TJ. Rooney JP, et al. Among authors: begley tj, begley u. Genomics. 2011 Mar;97(3):133-47. doi: 10.1016/j.ygeno.2010.12.005. Epub 2010 Dec 30. Genomics. 2011. PMID: 21195161 Free PMC article.

2

Methanobacterium thermoformicicum thymine DNA mismatch glycosylase: conversion of an N-glycosylase to an AP lyase.

Begley TJ, Cunningham RP. Begley TJ, et al. Protein Eng. 1999 Apr;12(4):333-40. doi: 10.1093/protein/12.4.333. Protein Eng. 1999. PMID: 10325404

3

A new member of the endonuclease III family of DNA repair enzymes that removes methylated purines from DNA.

Begley TJ, Haas BJ, Noel J, Shekhtman A, Williams WA, Cunningham RP. Begley TJ, et al. Curr Biol. 1999 Jun 17;9(12):653-6. doi: 10.1016/s0960-9822(99)80288-7. Curr Biol. 1999. PMID: 10375529 Free article.

4

Structure and activity of a thermostable thymine-DNA glycosylase: evidence for base twisting to remove mismatched normal DNA bases.

Mol CD, Arvai AS, Begley TJ, Cunningham RP, Tainer JA. Mol CD, et al. Among authors: begley tj. J Mol Biol. 2002 Jan 18;315(3):373-84. doi: 10.1006/jmbi.2001.5264. J Mol Biol. 2002. PMID: 11786018

5

Kinetics and binding of the thymine-DNA mismatch glycosylase, Mig-Mth, with mismatch-containing DNA substrates.

Begley TJ, Haas BJ, Morales JC, Kool ET, Cunningham RP. Begley TJ, et al. DNA Repair (Amst). 2003 Jan 2;2(1):107-20. doi: 10.1016/s1568-7864(02)00190-8. DNA Repair (Amst). 2003. PMID: 12509271

6

The DNA-damage signature in Saccharomyces cerevisiae is associated with single-strand breaks in DNA.

Fry RC, DeMott MS, Cosgrove JP, Begley TJ, Samson LD, Dedon PC. Fry RC, et al. Among authors: begley tj. BMC Genomics. 2006 Dec 12;7:313. doi: 10.1186/1471-2164-7-313. BMC Genomics. 2006. PMID: 17163986 Free PMC article.

7

Trm9-catalyzed tRNA modifications link translation to the DNA damage response.

Begley U, Dyavaiah M, Patil A, Rooney JP, DiRenzo D, Young CM, Conklin DS, Zitomer RS, Begley TJ. Begley U, et al. Among authors: begley tj. Mol Cell. 2007 Dec 14;28(5):860-70. doi: 10.1016/j.molcel.2007.09.021. Mol Cell. 2007. PMID: 18082610 Free PMC article.

8

A molecular bar-coded DNA repair resource for pooled toxicogenomic screens.

Rooney JP, Patil A, Zappala MR, Conklin DS, Cunningham RP, Begley TJ. Rooney JP, et al. Among authors: begley tj. DNA Repair (Amst). 2008 Nov 1;7(11):1855-68. doi: 10.1016/j.dnarep.2008.07.013. Epub 2008 Sep 10. DNA Repair (Amst). 2008. PMID: 18723126 Free PMC article.

9

Systems based mapping demonstrates that recovery from alkylation damage requires DNA repair, RNA processing, and translation associated networks.

Rooney JP, George AD, Patil A, Begley U, Bessette E, Zappala MR, Huang X, Conklin DS, Cunningham RP, Begley TJ. Rooney JP, et al. Among authors: begley tj, begley u. Genomics. 2009 Jan;93(1):42-51. doi: 10.1016/j.ygeno.2008.09.001. Epub 2008 Oct 16. Genomics. 2009. PMID: 18824089 Free PMC article.

10

A genome-wide screen in Saccharomyces cerevisiae reveals pathways affected by arsenic toxicity.

Zhou X, Arita A, Ellen TP, Liu X, Bai J, Rooney JP, Kurtz AD, Klein CB, Dai W, Begley TJ, Costa M. Zhou X, et al. Among authors: begley tj. Genomics. 2009 Nov;94(5):294-307. doi: 10.1016/j.ygeno.2009.07.003. Epub 2009 Jul 22. Genomics. 2009. PMID: 19631266 Free PMC article.

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