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Glucose-insulin-potassium reduces the incidence of low cardiac output episodes after aortic valve replacement for aortic stenosis in patients with left ventricular hypertrophy: results from the Hypertrophy, Insulin, Glucose, and Electrolytes (HINGE) trial.
Howell NJ, Ashrafian H, Drury NE, Ranasinghe AM, Contractor H, Isackson H, Calvert M, Williams LK, Freemantle N, Quinn DW, Green D, Frenneaux M, Bonser RS, Mascaro JG, Graham TR, Rooney SJ, Wilson IC, Pagano D. Howell NJ, et al. Among authors: ashrafian h. Circulation. 2011 Jan 18;123(2):170-7. doi: 10.1161/CIRCULATIONAHA.110.945170. Epub 2011 Jan 3. Circulation. 2011. PMID: 21200004 Clinical Trial.
Metabolic mechanisms in heart failure.
Ashrafian H, Frenneaux MP, Opie LH. Ashrafian H, et al. Circulation. 2007 Jul 24;116(4):434-48. doi: 10.1161/CIRCULATIONAHA.107.702795. Circulation. 2007. PMID: 17646594 Review.
Metabolic modulator perhexiline corrects energy deficiency and improves exercise capacity in symptomatic hypertrophic cardiomyopathy.
Abozguia K, Elliott P, McKenna W, Phan TT, Nallur-Shivu G, Ahmed I, Maher AR, Kaur K, Taylor J, Henning A, Ashrafian H, Watkins H, Frenneaux M. Abozguia K, et al. Among authors: ashrafian h. Circulation. 2010 Oct 19;122(16):1562-9. doi: 10.1161/CIRCULATIONAHA.109.934059. Epub 2010 Oct 4. Circulation. 2010. PMID: 20921440 Clinical Trial.
Heart failure with preserved ejection fraction is characterized by dynamic impairment of active relaxation and contraction of the left ventricle on exercise and associated with myocardial energy deficiency.
Phan TT, Abozguia K, Nallur Shivu G, Mahadevan G, Ahmed I, Williams L, Dwivedi G, Patel K, Steendijk P, Ashrafian H, Henning A, Frenneaux M. Phan TT, et al. Among authors: ashrafian h. J Am Coll Cardiol. 2009 Jul 28;54(5):402-9. doi: 10.1016/j.jacc.2009.05.012. J Am Coll Cardiol. 2009. PMID: 19628114 Free article.
Effect of Selective Heart Rate Slowing in Heart Failure With Preserved Ejection Fraction.
Pal N, Sivaswamy N, Mahmod M, Yavari A, Rudd A, Singh S, Dawson DK, Francis JM, Dwight JS, Watkins H, Neubauer S, Frenneaux M, Ashrafian H. Pal N, et al. Among authors: ashrafian h. Circulation. 2015 Nov 3;132(18):1719-25. doi: 10.1161/CIRCULATIONAHA.115.017119. Epub 2015 Sep 2. Circulation. 2015. PMID: 26338956 Free PMC article. Clinical Trial.
Perhexiline.
Ashrafian H, Horowitz JD, Frenneaux MP. Ashrafian H, et al. Cardiovasc Drug Rev. 2007 Spring;25(1):76-97. doi: 10.1111/j.1527-3466.2007.00006.x. Cardiovasc Drug Rev. 2007. PMID: 17445089 Review.
Hypoxic modulation of exogenous nitrite-induced vasodilation in humans.
Maher AR, Milsom AB, Gunaruwan P, Abozguia K, Ahmed I, Weaver RA, Thomas P, Ashrafian H, Born GV, James PE, Frenneaux MP. Maher AR, et al. Among authors: ashrafian h. Circulation. 2008 Feb 5;117(5):670-7. doi: 10.1161/CIRCULATIONAHA.107.719591. Epub 2008 Jan 22. Circulation. 2008. PMID: 18212289 Free article.
552 results