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Inhibitors of foot and mouth disease virus targeting a novel pocket of the RNA-dependent RNA polymerase.
Durk RC, Singh K, Cornelison CA, Rai DK, Matzek KB, Leslie MD, Schafer E, Marchand B, Adedeji A, Michailidis E, Dorst CA, Moran J, Pautler C, Rodriguez LL, McIntosh MA, Rieder E, Sarafianos SG. Durk RC, et al. Among authors: singh k. PLoS One. 2010 Dec 21;5(12):e15049. doi: 10.1371/journal.pone.0015049. PLoS One. 2010. PMID: 21203539 Free PMC article.
Biochemical mechanism of HIV-1 resistance to rilpivirine.
Singh K, Marchand B, Rai DK, Sharma B, Michailidis E, Ryan EM, Matzek KB, Leslie MD, Hagedorn AN, Li Z, Norden PR, Hachiya A, Parniak MA, Xu HT, Wainberg MA, Sarafianos SG. Singh K, et al. J Biol Chem. 2012 Nov 2;287(45):38110-23. doi: 10.1074/jbc.M112.398180. Epub 2012 Sep 6. J Biol Chem. 2012. PMID: 22955279 Free PMC article.
Hypersusceptibility mechanism of Tenofovir-resistant HIV to EFdA.
Michailidis E, Ryan EM, Hachiya A, Kirby KA, Marchand B, Leslie MD, Huber AD, Ong YT, Jackson JC, Singh K, Kodama EN, Mitsuya H, Parniak MA, Sarafianos SG. Michailidis E, et al. Among authors: singh k. Retrovirology. 2013 Jun 24;10:65. doi: 10.1186/1742-4690-10-65. Retrovirology. 2013. PMID: 23800377 Free PMC article.
Evaluation of SSYA10-001 as a replication inhibitor of severe acute respiratory syndrome, mouse hepatitis, and Middle East respiratory syndrome coronaviruses.
Adedeji AO, Singh K, Kassim A, Coleman CM, Elliott R, Weiss SR, Frieman MB, Sarafianos SG. Adedeji AO, et al. Among authors: singh k. Antimicrob Agents Chemother. 2014 Aug;58(8):4894-8. doi: 10.1128/AAC.02994-14. Epub 2014 May 19. Antimicrob Agents Chemother. 2014. PMID: 24841268 Free PMC article.
3-Hydroxypyrimidine-2,4-Diones as Novel Hepatitis B Virus Antivirals Targeting the Viral Ribonuclease H.
Huber AD, Michailidis E, Tang J, Puray-Chavez MN, Boftsi M, Wolf JJ, Boschert KN, Sheridan MA, Leslie MD, Kirby KA, Singh K, Mitsuya H, Parniak MA, Wang Z, Sarafianos SG. Huber AD, et al. Among authors: singh k. Antimicrob Agents Chemother. 2017 May 24;61(6):e00245-17. doi: 10.1128/AAC.00245-17. Print 2017 Jun. Antimicrob Agents Chemother. 2017. PMID: 28320718 Free PMC article.
9,996 results