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Gene targeting in human pluripotent cells.
Hockemeyer D, Jaenisch R. Hockemeyer D, et al. Cold Spring Harb Symp Quant Biol. 2010;75:201-9. doi: 10.1101/sqb.2010.75.021. Epub 2011 Jan 5. Cold Spring Harb Symp Quant Biol. 2010. PMID: 21209393 Review.
Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome.
DeKelver RC, Choi VM, Moehle EA, Paschon DE, Hockemeyer D, Meijsing SH, Sancak Y, Cui X, Steine EJ, Miller JC, Tam P, Bartsevich VV, Meng X, Rupniewski I, Gopalan SM, Sun HC, Pitz KJ, Rock JM, Zhang L, Davis GD, Rebar EJ, Cheeseman IM, Yamamoto KR, Sabatini DM, Jaenisch R, Gregory PD, Urnov FD. DeKelver RC, et al. Among authors: hockemeyer d. Genome Res. 2010 Aug;20(8):1133-42. doi: 10.1101/gr.106773.110. Epub 2010 May 27. Genome Res. 2010. PMID: 20508142 Free PMC article.
Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats.
Hargus G, Cooper O, Deleidi M, Levy A, Lee K, Marlow E, Yow A, Soldner F, Hockemeyer D, Hallett PJ, Osborn T, Jaenisch R, Isacson O. Hargus G, et al. Among authors: hockemeyer d. Proc Natl Acad Sci U S A. 2010 Sep 7;107(36):15921-6. doi: 10.1073/pnas.1010209107. Epub 2010 Aug 23. Proc Natl Acad Sci U S A. 2010. PMID: 20798034 Free PMC article.
Genetic engineering of human pluripotent cells using TALE nucleases.
Hockemeyer D, Wang H, Kiani S, Lai CS, Gao Q, Cassady JP, Cost GJ, Zhang L, Santiago Y, Miller JC, Zeitler B, Cherone JM, Meng X, Hinkley SJ, Rebar EJ, Gregory PD, Urnov FD, Jaenisch R. Hockemeyer D, et al. Nat Biotechnol. 2011 Jul 7;29(8):731-4. doi: 10.1038/nbt.1927. Nat Biotechnol. 2011. PMID: 21738127 Free PMC article.
Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations.
Soldner F, Laganière J, Cheng AW, Hockemeyer D, Gao Q, Alagappan R, Khurana V, Golbe LI, Myers RH, Lindquist S, Zhang L, Guschin D, Fong LK, Vu BJ, Meng X, Urnov FD, Rebar EJ, Gregory PD, Zhang HS, Jaenisch R. Soldner F, et al. Among authors: hockemeyer d. Cell. 2011 Jul 22;146(2):318-31. doi: 10.1016/j.cell.2011.06.019. Epub 2011 Jul 14. Cell. 2011. PMID: 21757228 Free PMC article.
68 results