Gu LQ - Search Results

1

Pharmacophore-based discovery of triaryl-substituted imidazole as new telomeric G-quadruplex ligand.

Chen SB, Tan JH, Ou TM, Huang SL, An LK, Luo HB, Li D, Gu LQ, Huang ZS. Chen SB, et al. Among authors: gu lq. Bioorg Med Chem Lett. 2011 Feb 1;21(3):1004-9. doi: 10.1016/j.bmcl.2010.12.019. Epub 2010 Dec 10. Bioorg Med Chem Lett. 2011. PMID: 21211968

2

Synthesis and evaluation of quindoline derivatives as G-quadruplex inducing and stabilizing ligands and potential inhibitors of telomerase.

Zhou JL, Lu YJ, Ou TM, Zhou JM, Huang ZS, Zhu XF, Du CJ, Bu XZ, Ma L, Gu LQ, Li YM, Chan AS. Zhou JL, et al. Among authors: gu lq. J Med Chem. 2005 Nov 17;48(23):7315-21. doi: 10.1021/jm050041b. J Med Chem. 2005. PMID: 16279791

3

Stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc by quindoline derivatives.

Ou TM, Lu YJ, Zhang C, Huang ZS, Wang XD, Tan JH, Chen Y, Ma DL, Wong KY, Tang JC, Chan AS, Gu LQ. Ou TM, et al. Among authors: gu lq. J Med Chem. 2007 Apr 5;50(7):1465-74. doi: 10.1021/jm0610088. Epub 2007 Mar 9. J Med Chem. 2007. PMID: 17346034

4

Derivatives of oxoisoaporphine alkaloids: a novel class of selective acetylcholinesterase inhibitors.

Tang H, Ning FX, Wei YB, Huang SL, Huang ZS, Chan AS, Gu LQ. Tang H, et al. Among authors: gu lq. Bioorg Med Chem Lett. 2007 Jul 1;17(13):3765-8. doi: 10.1016/j.bmcl.2007.04.015. Epub 2007 Apr 10. Bioorg Med Chem Lett. 2007. PMID: 17451950

5

9-Substituted berberine derivatives as G-quadruplex stabilizing ligands in telomeric DNA.

Zhang WJ, Ou TM, Lu YJ, Huang YY, Wu WB, Huang ZS, Zhou JL, Wong KY, Gu LQ. Zhang WJ, et al. Among authors: gu lq. Bioorg Med Chem. 2007 Aug 15;15(16):5493-501. doi: 10.1016/j.bmc.2007.05.050. Epub 2007 May 25. Bioorg Med Chem. 2007. PMID: 17574421

6

Synthesis, cytotoxic activities and structure-activity relationships of topoisomerase I inhibitors: indolizinoquinoline-5,12-dione derivatives.

Cheng Y, An LK, Wu N, Wang XD, Bu XZ, Huang ZS, Gu LQ. Cheng Y, et al. Among authors: gu lq. Bioorg Med Chem. 2008 Apr 15;16(8):4617-25. doi: 10.1016/j.bmc.2008.02.036. Epub 2008 Feb 15. Bioorg Med Chem. 2008. PMID: 18296054

7

Design, synthesis and evaluation of isaindigotone derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors.

Pan L, Tan JH, Hou JQ, Huang SL, Gu LQ, Huang ZS. Pan L, et al. Among authors: gu lq. Bioorg Med Chem Lett. 2008 Jul 1;18(13):3790-3. doi: 10.1016/j.bmcl.2008.05.039. Epub 2008 May 16. Bioorg Med Chem Lett. 2008. PMID: 18524585

8

9-N-Substituted berberine derivatives: stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc.

Ma Y, Ou TM, Hou JQ, Lu YJ, Tan JH, Gu LQ, Huang ZS. Ma Y, et al. Among authors: gu lq. Bioorg Med Chem. 2008 Aug 15;16(16):7582-91. doi: 10.1016/j.bmc.2008.07.029. Epub 2008 Jul 18. Bioorg Med Chem. 2008. PMID: 18674916

9

Synthesis and evaluation of curcumin analogues as potential thioredoxin reductase inhibitors.

Qiu X, Liu Z, Shao WY, Liu X, Jing DP, Yu YJ, An LK, Huang SL, Bu XZ, Huang ZS, Gu LQ. Qiu X, et al. Among authors: gu lq. Bioorg Med Chem. 2008 Sep 1;16(17):8035-41. doi: 10.1016/j.bmc.2008.07.054. Epub 2008 Jul 24. Bioorg Med Chem. 2008. PMID: 18678491

10

5-N-methylated quindoline derivatives as telomeric g-quadruplex stabilizing ligands: effects of 5-N positive charge on quadruplex binding affinity and cell proliferation.

Lu YJ, Ou TM, Tan JH, Hou JQ, Shao WY, Peng D, Sun N, Wang XD, Wu WB, Bu XZ, Huang ZS, Ma DL, Wong KY, Gu LQ. Lu YJ, et al. Among authors: gu lq. J Med Chem. 2008 Oct 23;51(20):6381-92. doi: 10.1021/jm800497p. Epub 2008 Sep 27. J Med Chem. 2008. PMID: 18821749

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