Murphy BR - Search Results

1

Immune response to dengue virus and prospects for a vaccine.

Murphy BR, Whitehead SS. Murphy BR, et al. Annu Rev Immunol. 2011;29:587-619. doi: 10.1146/annurev-immunol-031210-101315. Annu Rev Immunol. 2011. PMID: 21219187 Review.

2

Paired charge-to-alanine mutagenesis of dengue virus type 4 NS5 generates mutants with temperature-sensitive, host range, and mouse attenuation phenotypes.

Hanley KA, Lee JJ, Blaney JE Jr, Murphy BR, Whitehead SS. Hanley KA, et al. Among authors: murphy br. J Virol. 2002 Jan;76(2):525-31. doi: 10.1128/jvi.76.2.525-531.2002. J Virol. 2002. PMID: 11752143 Free PMC article.

3

Genetic basis of attenuation of dengue virus type 4 small plaque mutants with restricted replication in suckling mice and in SCID mice transplanted with human liver cells.

Blaney JE Jr, Johnson DH, Manipon GG, Firestone CY, Hanson CT, Murphy BR, Whitehead SS. Blaney JE Jr, et al. Among authors: murphy br. Virology. 2002 Aug 15;300(1):125-39. doi: 10.1006/viro.2002.1528. Virology. 2002. PMID: 12202213 Free article.

4

A live, attenuated dengue virus type 1 vaccine candidate with a 30-nucleotide deletion in the 3' untranslated region is highly attenuated and immunogenic in monkeys.

Whitehead SS, Falgout B, Hanley KA, Blaney JE Jr, Markoff L, Murphy BR. Whitehead SS, et al. Among authors: murphy br. J Virol. 2003 Jan;77(2):1653-7. doi: 10.1128/jvi.77.2.1653-1657.2003. J Virol. 2003. PMID: 12502885 Free PMC article.

5

A trade-off in replication in mosquito versus mammalian systems conferred by a point mutation in the NS4B protein of dengue virus type 4.

Hanley KA, Manlucu LR, Gilmore LE, Blaney JE Jr, Hanson CT, Murphy BR, Whitehead SS. Hanley KA, et al. Among authors: murphy br. Virology. 2003 Jul 20;312(1):222-32. doi: 10.1016/s0042-6822(03)00197-1. Virology. 2003. PMID: 12890635 Free article.

6

Substitution of the structural genes of dengue virus type 4 with those of type 2 results in chimeric vaccine candidates which are attenuated for mosquitoes, mice, and rhesus monkeys.

Whitehead SS, Hanley KA, Blaney JE Jr, Gilmore LE, Elkins WR, Murphy BR. Whitehead SS, et al. Among authors: murphy br. Vaccine. 2003 Oct 1;21(27-30):4307-16. doi: 10.1016/s0264-410x(03)00488-2. Vaccine. 2003. PMID: 14505913

7

Mutations which enhance the replication of dengue virus type 4 and an antigenic chimeric dengue virus type 2/4 vaccine candidate in Vero cells.

Blaney JE Jr, Manipon GG, Firestone CY, Johnson DH, Hanson CT, Murphy BR, Whitehead SS. Blaney JE Jr, et al. Among authors: murphy br. Vaccine. 2003 Oct 1;21(27-30):4317-27. doi: 10.1016/s0264-410x(03)00487-0. Vaccine. 2003. PMID: 14505914

8

Introduction of mutations into the non-structural genes or 3' untranslated region of an attenuated dengue virus type 4 vaccine candidate further decreases replication in rhesus monkeys while retaining protective immunity.

Hanley KA, Manlucu LR, Manipon GG, Hanson CT, Whitehead SS, Murphy BR, Blaney JE Jr. Hanley KA, et al. Among authors: murphy br. Vaccine. 2004 Sep 3;22(25-26):3440-8. doi: 10.1016/j.vaccine.2004.02.031. Vaccine. 2004. PMID: 15308370

9

Vaccine candidates derived from a novel infectious cDNA clone of an American genotype dengue virus type 2.

Blaney JE Jr, Hanson CT, Hanley KA, Murphy BR, Whitehead SS. Blaney JE Jr, et al. Among authors: murphy br. BMC Infect Dis. 2004 Oct 4;4:39. doi: 10.1186/1471-2334-4-39. BMC Infect Dis. 2004. PMID: 15461822 Free PMC article.

10

Genetically modified, live attenuated dengue virus type 3 vaccine candidates.

Blaney JE Jr, Hanson CT, Firestone CY, Hanley KA, Murphy BR, Whitehead SS. Blaney JE Jr, et al. Among authors: murphy br. Am J Trop Med Hyg. 2004 Dec;71(6):811-21. Am J Trop Med Hyg. 2004. PMID: 15642976

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