Turkson J - Search Results

1

Identification of Purine-Scaffold Small-Molecule Inhibitors of Stat3 Activation by QSAR Studies.

Shahani VM, Yue P, Haftchenary S, Zhao W, Lukkarila JL, Zhang X, Ball D, Nona C, Gunning PT, Turkson J. Shahani VM, et al. Among authors: turkson j. ACS Med Chem Lett. 2011 Jan 13;2(1):79-84. doi: 10.1021/ml100224d. Epub 2010 Oct 25. ACS Med Chem Lett. 2011. Retraction in: ACS Med Chem Lett. 2023 Sep 19;14(10):1482. doi: 10.1021/acsmedchemlett.3c00405 PMID: 21243039 Free PMC article. Retracted.

2

Isoform selective inhibition of STAT1 or STAT3 homo-dimerization via peptidomimetic probes: structural recognition of STAT SH2 domains.

Gunning PT, Katt WP, Glenn M, Siddiquee K, Kim JS, Jove R, Sebti SM, Turkson J, Hamilton AD. Gunning PT, et al. Among authors: turkson j. Bioorg Med Chem Lett. 2007 Apr 1;17(7):1875-8. doi: 10.1016/j.bmcl.2007.01.077. Epub 2007 Jan 27. Bioorg Med Chem Lett. 2007. PMID: 17336521

3

An oxazole-based small-molecule Stat3 inhibitor modulates Stat3 stability and processing and induces antitumor cell effects.

Siddiquee KA, Gunning PT, Glenn M, Katt WP, Zhang S, Schrock C, Sebti SM, Jove R, Hamilton AD, Turkson J. Siddiquee KA, et al. Among authors: turkson j. ACS Chem Biol. 2007 Dec 21;2(12):787-98. doi: 10.1021/cb7001973. ACS Chem Biol. 2007. PMID: 18154266

4

Molecular approaches towards the inhibition of the signal transducer and activator of transcription 3 (Stat3) protein.

Fletcher S, Turkson J, Gunning PT. Fletcher S, et al. Among authors: turkson j. ChemMedChem. 2008 Aug;3(8):1159-68. doi: 10.1002/cmdc.200800123. ChemMedChem. 2008. PMID: 18683176 Free PMC article. Review. No abstract available.

5

Targeting protein-protein interactions: suppression of Stat3 dimerization with rationally designed small-molecule, nonpeptidic SH2 domain binders.

Gunning PT, Glenn MP, Siddiquee KA, Katt WP, Masson E, Sebti SM, Turkson J, Hamilton AD. Gunning PT, et al. Among authors: turkson j. Chembiochem. 2008 Nov 24;9(17):2800-3. doi: 10.1002/cbic.200800291. Chembiochem. 2008. PMID: 19006150 Free PMC article. No abstract available.

6

Targeting STAT3 in cancer: how successful are we?

Yue P, Turkson J. Yue P, et al. Among authors: turkson j. Expert Opin Investig Drugs. 2009 Jan;18(1):45-56. doi: 10.1517/13543780802565791. Expert Opin Investig Drugs. 2009. PMID: 19053881 Free PMC article. Review.

7

Disruption of transcriptionally active Stat3 dimers with non-phosphorylated, salicylic acid-based small molecules: potent in vitro and tumor cell activities.

Fletcher S, Singh J, Zhang X, Yue P, Page BD, Sharmeen S, Shahani VM, Zhao W, Schimmer AD, Turkson J, Gunning PT. Fletcher S, et al. Among authors: turkson j. Chembiochem. 2009 Aug 17;10(12):1959-64. doi: 10.1002/cbic.200900172. Chembiochem. 2009. PMID: 19644994 Free PMC article. No abstract available.

8

A novel small-molecule disrupts Stat3 SH2 domain-phosphotyrosine interactions and Stat3-dependent tumor processes.

Zhang X, Yue P, Fletcher S, Zhao W, Gunning PT, Turkson J. Zhang X, et al. Among authors: turkson j. Biochem Pharmacol. 2010 May 15;79(10):1398-409. doi: 10.1016/j.bcp.2010.01.001. Epub 2010 Jan 11. Biochem Pharmacol. 2010. PMID: 20067773 Free PMC article.

9

Enhanced sensitivity of pancreatic cancer cells to concurrent inhibition of aberrant signal transducer and activator of transcription 3 and epidermal growth factor receptor or Src.

Jaganathan S, Yue P, Turkson J. Jaganathan S, et al. Among authors: turkson j. J Pharmacol Exp Ther. 2010 May;333(2):373-81. doi: 10.1124/jpet.109.162669. Epub 2010 Jan 25. J Pharmacol Exp Ther. 2010. PMID: 20100905 Free PMC article.

10

Coordination complex SH2 domain proteomimetics: an alternative approach to disrupting oncogenic protein-protein interactions.

Drewry JA, Fletcher S, Yue P, Marushchak D, Zhao W, Sharmeen S, Zhang X, Schimmer AD, Gradinaru C, Turkson J, Gunning PT. Drewry JA, et al. Among authors: turkson j. Chem Commun (Camb). 2010 Feb 14;46(6):892-4. doi: 10.1039/b919608k. Epub 2009 Dec 1. Chem Commun (Camb). 2010. PMID: 20107641 Free PMC article.

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