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Pre-fibrillar alpha-synuclein variants with impaired beta-structure increase neurotoxicity in Parkinson's disease models.
Karpinar DP, Balija MB, Kügler S, Opazo F, Rezaei-Ghaleh N, Wender N, Kim HY, Taschenberger G, Falkenburger BH, Heise H, Kumar A, Riedel D, Fichtner L, Voigt A, Braus GH, Giller K, Becker S, Herzig A, Baldus M, Jäckle H, Eimer S, Schulz JB, Griesinger C, Zweckstetter M. Karpinar DP, et al. Among authors: voigt a. EMBO J. 2009 Oct 21;28(20):3256-68. doi: 10.1038/emboj.2009.257. Epub 2009 Sep 10. EMBO J. 2009. PMID: 19745811 Free PMC article.
Fas/CD95 regulatory protein Faim2 is neuroprotective after transient brain ischemia.
Reich A, Spering C, Gertz K, Harms C, Gerhardt E, Kronenberg G, Nave KA, Schwab M, Tauber SC, Drinkut A, Harms K, Beier CP, Voigt A, Göbbels S, Endres M, Schulz JB. Reich A, et al. Among authors: voigt a. J Neurosci. 2011 Jan 5;31(1):225-33. doi: 10.1523/JNEUROSCI.2188-10.2011. J Neurosci. 2011. PMID: 21209208 Free PMC article.
Quantitative interaction proteomics of neurodegenerative disease proteins.
Hosp F, Vossfeldt H, Heinig M, Vasiljevic D, Arumughan A, Wyler E; Genetic and Environmental Risk for Alzheimer’s Disease GERAD1 Consortium; Landthaler M, Hubner N, Wanker EE, Lannfelt L, Ingelsson M, Lalowski M, Voigt A, Selbach M. Hosp F, et al. Among authors: voigt a. Cell Rep. 2015 May 19;11(7):1134-46. doi: 10.1016/j.celrep.2015.04.030. Epub 2015 May 7. Cell Rep. 2015. PMID: 25959826 Free PMC article.
Monitoring α-synuclein multimerization in vivo.
Prasad V, Wasser Y, Hans F, Goswami A, Katona I, Outeiro TF, Kahle PJ, Schulz JB, Voigt A. Prasad V, et al. Among authors: voigt a. FASEB J. 2019 Feb;33(2):2116-2131. doi: 10.1096/fj.201800148RRR. Epub 2018 Sep 25. FASEB J. 2019. PMID: 30252534
Here, we used the powerful genetics of Drosophila melanogaster and developed an in vivo assay to monitor alpha-Syn accumulation by using a bimolecular fluorescence complementation assay. We found that both genetic and pharmacologic manipulations affected alpha-Syn accumula …
Here, we used the powerful genetics of Drosophila melanogaster and developed an in vivo assay to monitor alpha-Syn accumulation by using …
566 results