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The type IV phosphodiesterase inhibitor rolipram induces expression of the cell cycle inhibitors p21(Cip1) and p27(Kip1), resulting in growth inhibition, increased differentiation, and subsequent apoptosis of malignant A-172 glioma cells.
Chen TC, Wadsten P, Su S, Rawlinson N, Hofman FM, Hill CK, Schönthal AH. Chen TC, et al. Among authors: schonthal ah. Cancer Biol Ther. 2002 May-Jun;1(3):268-76. doi: 10.4161/cbt.80. Cancer Biol Ther. 2002. PMID: 12432276 Free article.
Downregulation of survivin expression and concomitant induction of apoptosis by celecoxib and its non-cyclooxygenase-2-inhibitory analog, dimethyl-celecoxib (DMC), in tumor cells in vitro and in vivo.
Pyrko P, Soriano N, Kardosh A, Liu YT, Uddin J, Petasis NA, Hofman FM, Chen CS, Chen TC, Schönthal AH. Pyrko P, et al. Among authors: schonthal ah. Mol Cancer. 2006 May 18;5:19. doi: 10.1186/1476-4598-5-19. Mol Cancer. 2006. PMID: 16707021 Free PMC article.
171 results