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107 results

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Page 1
High concentration electrophysiology-based fragment screen: discovery of novel acid-sensing ion channel 3 (ASIC3) inhibitors.
Wolkenberg SE, Zhao Z, Mulhearn JJ, Harrison ST, Sanders JM, Cato MJ, Jovanovska A, Panigel J, Cook SP, Henze DA, Kane SA, Hartman GD, Barrow JC. Wolkenberg SE, et al. Among authors: cook sp. Bioorg Med Chem Lett. 2011 May 1;21(9):2646-9. doi: 10.1016/j.bmcl.2010.12.115. Epub 2010 Dec 28. Bioorg Med Chem Lett. 2011. PMID: 21257308
Amiloride derived inhibitors of acid-sensing ion channel-3 (ASIC3).
Kuduk SD, Di Marco CN, Chang RK, Dipardo RM, Cook SP, Cato MJ, Jovanovska A, Urban MO, Leitl M, Spencer RH, Kane SA, Bilodeau MT, Hartman GD, Bock MG. Kuduk SD, et al. Among authors: cook sp. Bioorg Med Chem Lett. 2009 May 1;19(9):2514-8. doi: 10.1016/j.bmcl.2009.03.029. Epub 2009 Mar 14. Bioorg Med Chem Lett. 2009. PMID: 19339181
Amidine derived inhibitors of acid-sensing ion channel-3 (ASIC3).
Kuduk SD, Chang RK, Wai JM, Di Marco CN, Cofre V, DiPardo RM, Cook SP, Cato MJ, Jovanovska A, Urban MO, Leitl M, Spencer RH, Kane SA, Hartman GD, Bilodeau MT. Kuduk SD, et al. Among authors: cook sp. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4059-63. doi: 10.1016/j.bmcl.2009.06.021. Epub 2009 Jun 13. Bioorg Med Chem Lett. 2009. PMID: 19553111
Identification of non-amidine inhibitors of acid-sensing ion channel-3 (ASIC3).
Kuduk SD, Chang RK, Di Marco CN, Dipardo RM, Cook SP, Cato MJ, Jovanovska A, Urban MO, Leitl M, Spencer RH, Kane SA, Hartman GD, Bilodeau MT. Kuduk SD, et al. Among authors: cook sp. Bioorg Med Chem Lett. 2011 Jul 15;21(14):4255-8. doi: 10.1016/j.bmcl.2011.05.064. Epub 2011 May 27. Bioorg Med Chem Lett. 2011. PMID: 21669528
Identification of second-generation P2X3 antagonists for treatment of pain.
Ginnetti AT, Paone DV, Stauffer SR, Potteiger CM, Shaw AW, Deng J, Mulhearn JJ, Nguyen DN, Segerdell C, Anquandah J, Calamari A, Cheng G, Leitl MD, Liang A, Moore E, Panigel J, Urban M, Wang J, Fillgrove K, Tang C, Cook S, Kane S, Salvatore CA, Graham SL, Burgey CS. Ginnetti AT, et al. Bioorg Med Chem Lett. 2018 May 1;28(8):1392-1396. doi: 10.1016/j.bmcl.2018.02.039. Epub 2018 Feb 21. Bioorg Med Chem Lett. 2018. PMID: 29548573
Synthesis, structure-activity relationship, and pharmacological profile of analogs of the ASIC-3 inhibitor A-317567.
Kuduk SD, Di Marco CN, Bodmer-Narkevitch V, Cook SP, Cato MJ, Jovanovska A, Urban MO, Leitl M, Sain N, Liang A, Spencer RH, Kane SA, Hartman GD, Bilodeau MT. Kuduk SD, et al. Among authors: cook sp. ACS Chem Neurosci. 2010 Jan 20;1(1):19-24. doi: 10.1021/cn9000186. Epub 2009 Oct 6. ACS Chem Neurosci. 2010. PMID: 22778804 Free PMC article.
Metal-free, photoinduced remote C(sp3)-H borylation.
He J, Cook SP. He J, et al. Among authors: cook sp. Chem Sci. 2023 Aug 22;14(35):9476-9481. doi: 10.1039/d3sc03048b. eCollection 2023 Sep 13. Chem Sci. 2023. PMID: 37712044 Free PMC article.
107 results