Wittinghofer A - Search Results

1

The P-loop--a common motif in ATP- and GTP-binding proteins.

Saraste M, Sibbald PR, Wittinghofer A. Saraste M, et al. Among authors: wittinghofer a. Trends Biochem Sci. 1990 Nov;15(11):430-4. doi: 10.1016/0968-0004(90)90281-f. Trends Biochem Sci. 1990. PMID: 2126155 Review.

2

The structure of Ras protein: a model for a universal molecular switch.

Wittinghofer A, Pai EF. Wittinghofer A, et al. Trends Biochem Sci. 1991 Oct;16(10):382-7. doi: 10.1016/0968-0004(91)90156-p. Trends Biochem Sci. 1991. PMID: 1785141 Review.

3

How Ras-related proteins talk to their effectors.

Wittinghofer A, Nassar N. Wittinghofer A, et al. Trends Biochem Sci. 1996 Dec;21(12):488-91. doi: 10.1016/s0968-0004(96)10064-5. Trends Biochem Sci. 1996. PMID: 9009833 Review.

4

Affinity of guanine nucleotide binding proteins for their ligands: facts and artefacts.

Goody RS, Frech M, Wittinghofer A. Goody RS, et al. Among authors: wittinghofer a. Trends Biochem Sci. 1991 Sep;16(9):327-8. doi: 10.1016/0968-0004(91)90134-h. Trends Biochem Sci. 1991. PMID: 1949151 No abstract available.

5

Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis.

Schlichting I, Almo SC, Rapp G, Wilson K, Petratos K, Lentfer A, Wittinghofer A, Kabsch W, Pai EF, Petsko GA, et al. Schlichting I, et al. Among authors: wittinghofer a. Nature. 1990 May 24;345(6273):309-15. doi: 10.1038/345309a0. Nature. 1990. PMID: 2111463

6

Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis.

Pai EF, Krengel U, Petsko GA, Goody RS, Kabsch W, Wittinghofer A. Pai EF, et al. Among authors: wittinghofer a. EMBO J. 1990 Aug;9(8):2351-9. doi: 10.1002/j.1460-2075.1990.tb07409.x. EMBO J. 1990. PMID: 2196171 Free PMC article.

7

GTPase-activating proteins: helping hands to complement an active site.

Scheffzek K, Ahmadian MR, Wittinghofer A. Scheffzek K, et al. Among authors: wittinghofer a. Trends Biochem Sci. 1998 Jul;23(7):257-62. doi: 10.1016/s0968-0004(98)01224-9. Trends Biochem Sci. 1998. PMID: 9697416 Review.

8

GEFs, GAPs, GDIs and effectors: taking a closer (3D) look at the regulation of Ras-related GTP-binding proteins.

Geyer M, Wittinghofer A. Geyer M, et al. Among authors: wittinghofer a. Curr Opin Struct Biol. 1997 Dec;7(6):786-92. doi: 10.1016/s0959-440x(97)80147-9. Curr Opin Struct Biol. 1997. PMID: 9434896 Review.

9

Structural insights into the small G-protein Arl13B and implications for Joubert syndrome.

Miertzschke M, Koerner C, Spoerner M, Wittinghofer A. Miertzschke M, et al. Among authors: wittinghofer a. Biochem J. 2014 Jan 15;457(2):301-11. doi: 10.1042/BJ20131097. Biochem J. 2014. PMID: 24168557

10

Model of the ran-RCC1 interaction using biochemical and docking experiments.

Azuma Y, Renault L, García-Ranea JA, Valencia A, Nishimoto T, Wittinghofer A. Azuma Y, et al. Among authors: wittinghofer a. J Mol Biol. 1999 Jun 18;289(4):1119-30. doi: 10.1006/jmbi.1999.2820. J Mol Biol. 1999. PMID: 10369786

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