Pei Y - Search Results

1

Effective siRNA delivery and target mRNA degradation using an amphipathic peptide to facilitate pH-dependent endosomal escape.

Bartz R, Fan H, Zhang J, Innocent N, Cherrin C, Beck SC, Pei Y, Momose A, Jadhav V, Tellers DM, Meng F, Crocker LS, Sepp-Lorenzino L, Barnett SF. Bartz R, et al. Among authors: pei y. Biochem J. 2011 Apr 15;435(2):475-87. doi: 10.1042/BJ20101021. Biochem J. 2011. PMID: 21265735

2

Quantitative evaluation of siRNA delivery in vivo.

Pei Y, Hancock PJ, Zhang H, Bartz R, Cherrin C, Innocent N, Pomerantz CJ, Seitzer J, Koser ML, Abrams MT, Xu Y, Kuklin NA, Burke PA, Sachs AB, Sepp-Lorenzino L, Barnett SF. Pei Y, et al. RNA. 2010 Dec;16(12):2553-63. doi: 10.1261/rna.2255810. Epub 2010 Oct 12. RNA. 2010. PMID: 20940339 Free PMC article.

3

5'-(E)-Vinylphosphonate: A Stable Phosphate Mimic Can Improve the RNAi Activity of siRNA-GalNAc Conjugates.

Parmar R, Willoughby JL, Liu J, Foster DJ, Brigham B, Theile CS, Charisse K, Akinc A, Guidry E, Pei Y, Strapps W, Cancilla M, Stanton MG, Rajeev KG, Sepp-Lorenzino L, Manoharan M, Meyers R, Maier MA, Jadhav V. Parmar R, et al. Among authors: pei y. Chembiochem. 2016 Jun 2;17(11):985-9. doi: 10.1002/cbic.201600130. Epub 2016 Apr 28. Chembiochem. 2016. PMID: 27121751

4

Systematic chemical modifications of single stranded siRNAs significantly improved CTNNB1 mRNA silencing.

Chang W, Pei Y, Guidry EN, Zewge D, Parish CA, Sherer EC, DiMuzio J, Zhang H, South VJ, Strapps WR, Sepp-Lorenzino L, Colletti SL, Stanton MG. Chang W, et al. Among authors: pei y. Bioorg Med Chem Lett. 2016 Sep 15;26(18):4513-4517. doi: 10.1016/j.bmcl.2016.07.064. Epub 2016 Jul 28. Bioorg Med Chem Lett. 2016. PMID: 27503684

5

Assessing the heterogeneity level in lipid nanoparticles for siRNA delivery: size-based separation, compositional heterogeneity, and impact on bioperformance.

Zhang J, Pei Y, Zhang H, Wang L, Arrington L, Zhang Y, Glass A, Leone AM. Zhang J, et al. Among authors: pei y. Mol Pharm. 2013 Jan 7;10(1):397-405. doi: 10.1021/mp3005337. Epub 2012 Dec 19. Mol Pharm. 2013. PMID: 23210488

6

Effect of biological matrix and sample preparation on qPCR quantitation of siRNA drugs in animal tissues.

Seitzer J, Zhang H, Koser M, Pei Y, Abrams M. Seitzer J, et al. Among authors: pei y. J Pharmacol Toxicol Methods. 2011 Mar-Apr;63(2):168-73. doi: 10.1016/j.vascn.2010.09.005. Epub 2010 Sep 25. J Pharmacol Toxicol Methods. 2011. PMID: 20884364

7

On the art of identifying effective and specific siRNAs.

Pei Y, Tuschl T. Pei Y, et al. Nat Methods. 2006 Sep;3(9):670-6. doi: 10.1038/nmeth911. Nat Methods. 2006. PMID: 16929310 Review.

8

Strand-specific 5'-O-methylation of siRNA duplexes controls guide strand selection and targeting specificity.

Chen PY, Weinmann L, Gaidatzis D, Pei Y, Zavolan M, Tuschl T, Meister G. Chen PY, et al. Among authors: pei y. RNA. 2008 Feb;14(2):263-74. doi: 10.1261/rna.789808. Epub 2007 Dec 19. RNA. 2008. PMID: 18094121 Free PMC article.

9

RNA-induced silencing complex-bound small interfering RNA is a determinant of RNA interference-mediated gene silencing in mice.

Wei J, Jones J, Kang J, Card A, Krimm M, Hancock P, Pei Y, Ason B, Payson E, Dubinina N, Cancilla M, Stroh M, Burchard J, Sachs AB, Hochman JH, Flanagan WM, Kuklin NA. Wei J, et al. Among authors: pei y. Mol Pharmacol. 2011 Jun;79(6):953-63. doi: 10.1124/mol.110.070409. Epub 2011 Mar 22. Mol Pharmacol. 2011. PMID: 21427169

10

Structural biology of RNA silencing and its functional implications.

Patel DJ, Ma JB, Yuan YR, Ye K, Pei Y, Kuryavyi V, Malinina L, Meister G, Tuschl T. Patel DJ, et al. Among authors: pei y. Cold Spring Harb Symp Quant Biol. 2006;71:81-93. doi: 10.1101/sqb.2006.71.053. Cold Spring Harb Symp Quant Biol. 2006. PMID: 17381284 Free PMC article. Review.

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