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Synthesis and biological evaluation of new nanomolar competitive inhibitors of Helicobacter pylori type II dehydroquinase. Structural details of the role of the aromatic moieties with essential residues.
Prazeres VF, Tizón L, Otero JM, Guardado-Calvo P, Llamas-Saiz AL, van Raaij MJ, Castedo L, Lamb H, Hawkins AR, González-Bello C. Prazeres VF, et al. Among authors: otero jm. J Med Chem. 2010 Jan 14;53(1):191-200. doi: 10.1021/jm9010466. J Med Chem. 2010. PMID: 19911771
An adamantyl amino acid containing gramicidin S analogue with broad spectrum antibacterial activity and reduced hemolytic activity.
Kapoerchan VV, Knijnenburg AD, Niamat M, Spalburg E, de Neeling AJ, Nibbering PH, Mars-Groenendijk RH, Noort D, Otero JM, Llamas-Saiz AL, van Raaij MJ, van der Marel GA, Overkleeft HS, Overhand M. Kapoerchan VV, et al. Among authors: otero jm. Chemistry. 2010 Oct 25;16(40):12174-81. doi: 10.1002/chem.201001686. Chemistry. 2010. PMID: 20848624
Structure of the bacteriophage T4 long tail fiber receptor-binding tip.
Bartual SG, Otero JM, Garcia-Doval C, Llamas-Saiz AL, Kahn R, Fox GC, van Raaij MJ. Bartual SG, et al. Among authors: otero jm. Proc Natl Acad Sci U S A. 2010 Nov 23;107(47):20287-92. doi: 10.1073/pnas.1011218107. Epub 2010 Nov 1. Proc Natl Acad Sci U S A. 2010. PMID: 21041684 Free PMC article.
Exploring the conformational and biological versatility of β-turn-modified gramicidin S by using sugar amino acid homologues that vary in ring size.
Knijnenburg AD, Tuin AW, Spalburg E, de Neeling AJ, Mars-Groenendijk RH, Noort D, Otero JM, Llamas-Saiz AL, van Raaij MJ, van der Marel GA, Overkleeft HS, Overhand M. Knijnenburg AD, et al. Among authors: otero jm. Chemistry. 2011 Mar 28;17(14):3995-4004. doi: 10.1002/chem.201002895. Epub 2011 Mar 1. Chemistry. 2011. PMID: 21365698
77 results