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CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy.
Azab AK, Runnels JM, Pitsillides C, Moreau AS, Azab F, Leleu X, Jia X, Wright R, Ospina B, Carlson AL, Alt C, Burwick N, Roccaro AM, Ngo HT, Farag M, Melhem MR, Sacco A, Munshi NC, Hideshima T, Rollins BJ, Anderson KC, Kung AL, Lin CP, Ghobrial IM. Azab AK, et al. Among authors: runnels jm. Blood. 2009 Apr 30;113(18):4341-51. doi: 10.1182/blood-2008-10-186668. Epub 2009 Jan 12. Blood. 2009. PMID: 19139079 Free PMC article.
RhoA and Rac1 GTPases play major and differential roles in stromal cell-derived factor-1-induced cell adhesion and chemotaxis in multiple myeloma.
Azab AK, Azab F, Blotta S, Pitsillides CM, Thompson B, Runnels JM, Roccaro AM, Ngo HT, Melhem MR, Sacco A, Jia X, Anderson KC, Lin CP, Rollins BJ, Ghobrial IM. Azab AK, et al. Among authors: runnels jm. Blood. 2009 Jul 16;114(3):619-29. doi: 10.1182/blood-2009-01-199281. Epub 2009 May 14. Blood. 2009. PMID: 19443661 Free PMC article.
Cell labeling approaches for fluorescence-based in vivo flow cytometry.
Pitsillides CM, Runnels JM, Spencer JA, Zhi L, Wu MX, Lin CP. Pitsillides CM, et al. Among authors: runnels jm. Cytometry A. 2011 Oct;79(10):758-65. doi: 10.1002/cyto.a.21125. Epub 2011 Sep 8. Cytometry A. 2011. PMID: 21905206 Free PMC article. Review.
Direct measurement of local oxygen concentration in the bone marrow of live animals.
Spencer JA, Ferraro F, Roussakis E, Klein A, Wu J, Runnels JM, Zaher W, Mortensen LJ, Alt C, Turcotte R, Yusuf R, Côté D, Vinogradov SA, Scadden DT, Lin CP. Spencer JA, et al. Among authors: runnels jm. Nature. 2014 Apr 10;508(7495):269-73. doi: 10.1038/nature13034. Epub 2014 Mar 2. Nature. 2014. PMID: 24590072 Free PMC article.
29 results