Chen L - Search Results

1

Design, synthesis and biological evaluation of novel 4-hydroxybenzene acrylic acid derivatives.

Mao JL, Ran XK, Tian JZ, Jiao B, Zhou HL, Chen L, Wang ZG. Mao JL, et al. Among authors: chen l. Bioorg Med Chem Lett. 2011 Mar 1;21(5):1549-53. doi: 10.1016/j.bmcl.2010.12.063. Epub 2010 Dec 23. Bioorg Med Chem Lett. 2011. PMID: 21288716

2

Synthesis and biological evaluation of nitric oxide-releasing derivatives of oleanolic acid as inhibitors of HepG2 cell apoptosis.

Chen L, Zhang Y, Kong X, Peng S, Tian J. Chen L, et al. Bioorg Med Chem Lett. 2007 Jun 1;17(11):2979-82. doi: 10.1016/j.bmcl.2007.03.068. Epub 2007 Mar 25. Bioorg Med Chem Lett. 2007. PMID: 17446070 Free PMC article.

3

Design, synthesis, and antihepatocellular carcinoma activity of nitric oxide releasing derivatives of oleanolic acid.

Chen L, Zhang Y, Kong X, Lan E, Huang Z, Peng S, Kaufman DL, Tian J. Chen L, et al. J Med Chem. 2008 Aug 14;51(15):4834-8. doi: 10.1021/jm800167u. Epub 2008 Jul 4. J Med Chem. 2008. PMID: 18598019 Free PMC article.

4

Studies on the structure-activity relationship of 1,3,3,4-tetra-substituted pyrrolidine embodied CCR5 receptor antagonists. Part 2: Discovery of highly potent anti-HIV agents.

Li B, Jones ED, Zhou E, Chen L, Baylis DC, Yu S, Wang M, He X, Coates JA, Rhodes DI, Pei G, Deadman JJ, Xie X, Ma D. Li B, et al. Among authors: chen l. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5334-6. doi: 10.1016/j.bmcl.2010.05.046. Epub 2010 May 19. Bioorg Med Chem Lett. 2010. PMID: 20674358

5

Synthesis and biological evaluation of farnesylthiosalicylamides as potential anti-tumor agents.

Ling Y, Wang Z, Zhu H, Wang X, Zhang W, Wang X, Chen L, Huang Z, Zhang Y. Ling Y, et al. Among authors: chen l. Bioorg Med Chem. 2014 Jan 1;22(1):374-80. doi: 10.1016/j.bmc.2013.11.013. Epub 2013 Nov 15. Bioorg Med Chem. 2014. PMID: 24300920

6

Design, synthesis, and anti-tumor activity of novel betulinic acid derivatives.

Liu JH, Tang J, Zhu ZF, Chen L. Liu JH, et al. Among authors: chen l. J Asian Nat Prod Res. 2014 Jan;16(1):34-42. doi: 10.1080/10286020.2013.870998. Epub 2013 Dec 19. J Asian Nat Prod Res. 2014. PMID: 24350921

7

Design, synthesis, and biological evaluation of dihydroartemisinin-fluoroquinolone conjugates as a novel type of potential antitubercular agents.

Zhou FW, Lei HS, Fan L, Jiang L, Liu J, Peng XM, Xu XR, Chen L, Zhou CH, Zou YY, Liu CP, He ZQ, Yang DC. Zhou FW, et al. Among authors: chen l. Bioorg Med Chem Lett. 2014 Apr 15;24(8):1912-7. doi: 10.1016/j.bmcl.2014.03.010. Epub 2014 Mar 17. Bioorg Med Chem Lett. 2014. PMID: 24684842

8

Quinazoline-1-deoxynojirimycin hybrids as high active dual inhibitors of EGFR and α-glucosidase.

Zhang Y, Gao H, Liu R, Liu J, Chen L, Li X, Zhao L, Wang W, Li B. Zhang Y, et al. Among authors: chen l. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4309-4313. doi: 10.1016/j.bmcl.2017.08.035. Epub 2017 Aug 18. Bioorg Med Chem Lett. 2017. PMID: 28838691

9

O²-(2,4-dinitrophenyl)diazeniumdiolates derivatives: Design, synthesis, cytotoxic evaluation and reversing MDR in MCF-7/ADR cells.

Li Q, Zou P, Sun J, Chen L. Li Q, et al. Among authors: chen l. Eur J Med Chem. 2018 Jan 1;143:732-744. doi: 10.1016/j.ejmech.2017.11.081. Eur J Med Chem. 2018. PMID: 29220794

10

Novel anticancer hybrids from diazen-1-ium-1,2-diolate nitric oxide donor and ROS inducer plumbagin: Design, synthesis and biological evaluations.

Bao N, Ou J, Li N, Zou P, Sun J, Chen L. Bao N, et al. Among authors: chen l. Eur J Med Chem. 2018 Jun 25;154:1-8. doi: 10.1016/j.ejmech.2018.04.047. Epub 2018 Apr 25. Eur J Med Chem. 2018. PMID: 29772386

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