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Clinical Trial Simulations Based on Genetic Stratification and the Natural History of a Functional Outcome Measure in Creutzfeldt-Jakob Disease.
Mead S, Burnell M, Lowe J, Thompson A, Lukic A, Porter MC, Carswell C, Kaski D, Kenny J, Mok TH, Bjurstrom N, Franko E, Gorham M, Druyeh R, Wadsworth JD, Jaunmuktane Z, Brandner S, Hyare H, Rudge P, Walker AS, Collinge J. Mead S, et al. Among authors: lowe j. JAMA Neurol. 2016 Apr;73(4):447-55. doi: 10.1001/jamaneurol.2015.4885. JAMA Neurol. 2016. PMID: 26902324 Free PMC article.
Quantitative EEG parameters correlate with the progression of human prion diseases.
Franko E, Wehner T, Joly O, Lowe J, Porter MC, Kenny J, Thompson A, Rudge P, Collinge J, Mead S. Franko E, et al. Among authors: lowe j. J Neurol Neurosurg Psychiatry. 2016 Oct;87(10):1061-7. doi: 10.1136/jnnp-2016-313501. Epub 2016 Jul 13. J Neurol Neurosurg Psychiatry. 2016. PMID: 27413165 Free PMC article. Review.
Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP.
Mead S, Uphill J, Beck J, Poulter M, Campbell T, Lowe J, Adamson G, Hummerich H, Klopp N, Rückert IM, Wichmann HE, Azazi D, Plagnol V, Pako WH, Whitfield J, Alpers MP, Whittaker J, Balding DJ, Zerr I, Kretzschmar H, Collinge J. Mead S, et al. Among authors: lowe j. Hum Mol Genet. 2012 Apr 15;21(8):1897-906. doi: 10.1093/hmg/ddr607. Epub 2011 Dec 30. Hum Mol Genet. 2012. PMID: 22210626 Free PMC article.
R47H TREM2 variant increases risk of typical early-onset Alzheimer's disease but not of prion or frontotemporal dementia.
Slattery CF, Beck JA, Harper L, Adamson G, Abdi Z, Uphill J, Campbell T, Druyeh R, Mahoney CJ, Rohrer JD, Kenny J, Lowe J, Leung KK, Barnes J, Clegg SL, Blair M, Nicholas JM, Guerreiro RJ, Rowe JB, Ponto C, Zerr I, Kretzschmar H, Gambetti P, Crutch SJ, Warren JD, Rossor MN, Fox NC, Collinge J, Schott JM, Mead S. Slattery CF, et al. Among authors: lowe j. Alzheimers Dement. 2014 Nov;10(6):602-608.e4. doi: 10.1016/j.jalz.2014.05.1751. Epub 2014 Aug 23. Alzheimers Dement. 2014. PMID: 25160042 Free PMC article.
The cognitive profile of prion disease: a prospective clinical and imaging study.
Caine D, Tinelli RJ, Hyare H, De Vita E, Lowe J, Lukic A, Thompson A, Porter MC, Cipolotti L, Rudge P, Collinge J, Mead S. Caine D, et al. Among authors: lowe j. Ann Clin Transl Neurol. 2015 May;2(5):548-58. doi: 10.1002/acn3.195. Epub 2015 Apr 7. Ann Clin Transl Neurol. 2015. PMID: 26000326 Free PMC article.
2,751 results