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Application of affinity selection-mass spectrometry assays to purification and affinity-based screening of the chemokine receptor CXCR4.
Whitehurst CE, Yao Z, Murphy D, Zhang M, Taremi S, Wojcik L, Strizki JM, Bracken JD, Cheng CC, Yang X, Shipps GW Jr, Ziebell M, Nickbarg E. Whitehurst CE, et al. Among authors: cheng cc. Comb Chem High Throughput Screen. 2012 Jul;15(6):473-85. doi: 10.2174/138620712800563945. Comb Chem High Throughput Screen. 2012. PMID: 22651846
Pyridine Carboxamides: Potent Palm Site Inhibitors of HCV NS5B Polymerase.
Cheng CC, Huang X, Shipps GW Jr, Wang YS, Wyss DF, Soucy KA, Jiang CK, Agrawal S, Ferrari E, He Z, Huang HC. Cheng CC, et al. ACS Med Chem Lett. 2010 Aug 17;1(9):466-71. doi: 10.1021/ml100128h. eCollection 2010 Dec 9. ACS Med Chem Lett. 2010. PMID: 24900232 Free PMC article.
Discovery and Hit-to-Lead Optimization of Non-ATP Competitive MK2 (MAPKAPK2) Inhibitors.
Huang X, Shipps GW Jr, Cheng CC, Spacciapoli P, Zhang X, McCoy MA, Wyss DF, Yang X, Achab A, Soucy K, Montavon DK, Murphy DM, Whitehurst CE. Huang X, et al. Among authors: cheng cc. ACS Med Chem Lett. 2011 Jun 24;2(8):632-7. doi: 10.1021/ml200113y. eCollection 2011 Aug 11. ACS Med Chem Lett. 2011. PMID: 24900358 Free PMC article.
Discovery and optimization of antibacterial AccC inhibitors.
Cheng CC, Shipps GW Jr, Yang Z, Sun B, Kawahata N, Soucy KA, Soriano A, Orth P, Xiao L, Mann P, Black T. Cheng CC, et al. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6507-14. doi: 10.1016/j.bmcl.2009.10.057. Epub 2009 Oct 28. Bioorg Med Chem Lett. 2009. PMID: 19875284
Discovery and characterization of orthosteric and allosteric muscarinic M2 acetylcholine receptor ligands by affinity selection-mass spectrometry.
Whitehurst CE, Nazef N, Annis DA, Hou Y, Murphy DM, Spacciapoli P, Yao Z, Ziebell MR, Cheng CC, Shipps GW Jr, Felsch JS, Lau D, Nash HM. Whitehurst CE, et al. Among authors: cheng cc. J Biomol Screen. 2006 Mar;11(2):194-207. doi: 10.1177/1087057105284340. Epub 2006 Feb 20. J Biomol Screen. 2006. PMID: 16490772
1,023 results