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Page 1
Cholestatic liver fibrosis and toxin-induced fibrosis are exacerbated in matrix metalloproteinase-2 deficient mice.
Onozuka I, Kakinuma S, Kamiya A, Miyoshi M, Sakamoto N, Kiyohashi K, Watanabe T, Funaoka Y, Ueyama M, Nakagawa M, Koshikawa N, Seiki M, Nakauchi H, Watanabe M. Onozuka I, et al. Among authors: kiyohashi k. Biochem Biophys Res Commun. 2011 Mar 4;406(1):134-40. doi: 10.1016/j.bbrc.2011.02.012. Epub 2011 Feb 12. Biochem Biophys Res Commun. 2011. PMID: 21300023
Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice.
Kiyohashi K, Kakinuma S, Kamiya A, Sakamoto N, Nitta S, Yamanaka H, Yoshino K, Fujiki J, Murakawa M, Kusano-Kitazume A, Shimizu H, Okamoto R, Azuma S, Nakagawa M, Asahina Y, Tanimizu N, Kikuchi A, Nakauchi H, Watanabe M. Kiyohashi K, et al. Hepatology. 2013 Jun;57(6):2502-13. doi: 10.1002/hep.26293. Epub 2013 May 14. Hepatology. 2013. PMID: 23386589
IL-6-mediated intersubgenotypic variation of interferon sensitivity in hepatitis C virus genotype 2a/2b chimeric clones.
Suda G, Sakamoto N, Itsui Y, Nakagawa M, Tasaka-Fujita M, Funaoka Y, Watanabe T, Nitta S, Kiyohashi K, Azuma S, Kakinuma S, Tsuchiya K, Imamura M, Hiraga N, Chayama K, Watanabe M. Suda G, et al. Among authors: kiyohashi k. Virology. 2010 Nov 10;407(1):80-90. doi: 10.1016/j.virol.2010.07.041. Epub 2010 Aug 25. Virology. 2010. PMID: 20797756 Free article.
Inhibitory effect of a triterpenoid compound, with or without alpha interferon, on hepatitis C virus infection.
Watanabe T, Sakamoto N, Nakagawa M, Kakinuma S, Itsui Y, Nishimura-Sakurai Y, Ueyama M, Funaoka Y, Kitazume A, Nitta S, Kiyohashi K, Murakawa M, Azuma S, Tsuchiya K, Oooka S, Watanabe M. Watanabe T, et al. Among authors: kiyohashi k. Antimicrob Agents Chemother. 2011 Jun;55(6):2537-45. doi: 10.1128/AAC.01780-10. Epub 2011 Mar 28. Antimicrob Agents Chemother. 2011. PMID: 21444704 Free PMC article.
Analysis of interferon signaling by infectious hepatitis C virus clones with substitutions of core amino acids 70 and 91.
Funaoka Y, Sakamoto N, Suda G, Itsui Y, Nakagawa M, Kakinuma S, Watanabe T, Mishima K, Ueyama M, Onozuka I, Nitta S, Kitazume A, Kiyohashi K, Murakawa M, Azuma S, Tsuchiya K, Watanabe M. Funaoka Y, et al. Among authors: kiyohashi k. J Virol. 2011 Jun;85(12):5986-94. doi: 10.1128/JVI.02583-10. Epub 2011 Apr 13. J Virol. 2011. PMID: 21490101 Free PMC article.
Serum interleukin-6 levels correlate with resistance to treatment of chronic hepatitis C infection with pegylated-interferon-α2b plus ribavirin.
Ueyama M, Nakagawa M, Sakamoto N, Onozuka I, Funaoka Y, Watanabe T, Nitta S, Kiyohashi K, Kitazume A, Murakawa M, Nishimura-Sakurai Y, Sekine-Osajima Y, Itsui Y, Azuma S, Kakinuma S, Watanabe M; Ochanomizu-Liver Conference Study Group. Ueyama M, et al. Among authors: kiyohashi k. Antivir Ther. 2011;16(7):1081-91. doi: 10.3851/IMP1864. Antivir Ther. 2011. PMID: 22024524
Association of ITPA gene variation and serum ribavirin concentration with a decline in blood cell concentrations during pegylated interferon-alpha plus ribavirin therapy for chronic hepatitis C.
Nakagawa M, Sakamoto N, Watanabe T, Nishimura-Sakurai Y, Onozuka I, Azuma S, Kakinuma S, Nitta S, Kiyohashi K, Kusano-Kitazume A, Murakawa M, Yoshino K, Itsui Y, Tanaka Y, Mizokami M, Watanabe M; Ochanomizu-Liver Conference Study Group. Nakagawa M, et al. Among authors: kiyohashi k. Hepatol Int. 2013 Mar;7(1):153-61. doi: 10.1007/s12072-012-9363-6. Epub 2012 Mar 21. Hepatol Int. 2013. PMID: 26201629
Identification of novel N-(morpholine-4-carbonyloxy) amidine compounds as potent inhibitors against hepatitis C virus replication.
Kusano-Kitazume A, Sakamoto N, Okuno Y, Sekine-Osajima Y, Nakagawa M, Kakinuma S, Kiyohashi K, Nitta S, Murakawa M, Azuma S, Nishimura-Sakurai Y, Hagiwara M, Watanabe M. Kusano-Kitazume A, et al. Among authors: kiyohashi k. Antimicrob Agents Chemother. 2012 Mar;56(3):1315-23. doi: 10.1128/AAC.05764-11. Epub 2011 Dec 27. Antimicrob Agents Chemother. 2012. PMID: 22203602 Free PMC article.
Cell culture and in vivo analyses of cytopathic hepatitis C virus mutants.
Mishima K, Sakamoto N, Sekine-Osajima Y, Nakagawa M, Itsui Y, Azuma S, Kakinuma S, Kiyohashi K, Kitazume A, Tsuchiya K, Imamura M, Hiraga N, Chayama K, Wakita T, Watanabe M. Mishima K, et al. Among authors: kiyohashi k. Virology. 2010 Sep 30;405(2):361-9. doi: 10.1016/j.virol.2010.06.020. Epub 2010 Jul 6. Virology. 2010. PMID: 20609455 Free article.