De Carvalho DD - Search Results

1

Nucleosomes containing methylated DNA stabilize DNA methyltransferases 3A/3B and ensure faithful epigenetic inheritance.

Sharma S, De Carvalho DD, Jeong S, Jones PA, Liang G. Sharma S, et al. Among authors: de carvalho dd. PLoS Genet. 2011 Feb 3;7(2):e1001286. doi: 10.1371/journal.pgen.1001286. PLoS Genet. 2011. PMID: 21304883 Free PMC article.

2

DNA methylation and cellular reprogramming.

De Carvalho DD, You JS, Jones PA. De Carvalho DD, et al. Trends Cell Biol. 2010 Oct;20(10):609-17. doi: 10.1016/j.tcb.2010.08.003. Epub 2010 Aug 31. Trends Cell Biol. 2010. PMID: 20810283 Free PMC article. Review.

3

Epigenetic modifications as therapeutic targets.

Kelly TK, De Carvalho DD, Jones PA. Kelly TK, et al. Among authors: de carvalho dd. Nat Biotechnol. 2010 Oct;28(10):1069-78. doi: 10.1038/nbt.1678. Nat Biotechnol. 2010. PMID: 20944599 Free PMC article. Review.

4

OCT4 establishes and maintains nucleosome-depleted regions that provide additional layers of epigenetic regulation of its target genes.

You JS, Kelly TK, De Carvalho DD, Taberlay PC, Liang G, Jones PA. You JS, et al. Among authors: de carvalho dd. Proc Natl Acad Sci U S A. 2011 Aug 30;108(35):14497-502. doi: 10.1073/pnas.1111309108. Epub 2011 Aug 15. Proc Natl Acad Sci U S A. 2011. PMID: 21844352 Free PMC article.

5

Polycomb-repressed genes have permissive enhancers that initiate reprogramming.

Taberlay PC, Kelly TK, Liu CC, You JS, De Carvalho DD, Miranda TB, Zhou XJ, Liang G, Jones PA. Taberlay PC, et al. Among authors: de carvalho dd. Cell. 2011 Dec 9;147(6):1283-94. doi: 10.1016/j.cell.2011.10.040. Cell. 2011. PMID: 22153073 Free PMC article.

6

DNA methylation screening identifies driver epigenetic events of cancer cell survival.

De Carvalho DD, Sharma S, You JS, Su SF, Taberlay PC, Kelly TK, Yang X, Liang G, Jones PA. De Carvalho DD, et al. Cancer Cell. 2012 May 15;21(5):655-667. doi: 10.1016/j.ccr.2012.03.045. Cancer Cell. 2012. PMID: 22624715 Free PMC article.

7

SNF5 is an essential executor of epigenetic regulation during differentiation.

You JS, De Carvalho DD, Dai C, Liu M, Pandiyan K, Zhou XJ, Liang G, Jones PA. You JS, et al. Among authors: de carvalho dd. PLoS Genet. 2013 Apr;9(4):e1003459. doi: 10.1371/journal.pgen.1003459. Epub 2013 Apr 25. PLoS Genet. 2013. PMID: 23637628 Free PMC article.

8

Gene body methylation can alter gene expression and is a therapeutic target in cancer.

Yang X, Han H, De Carvalho DD, Lay FD, Jones PA, Liang G. Yang X, et al. Among authors: de carvalho dd. Cancer Cell. 2014 Oct 13;26(4):577-90. doi: 10.1016/j.ccr.2014.07.028. Epub 2014 Sep 25. Cancer Cell. 2014. PMID: 25263941 Free PMC article.

9

DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts.

Roulois D, Loo Yau H, Singhania R, Wang Y, Danesh A, Shen SY, Han H, Liang G, Jones PA, Pugh TJ, O'Brien C, De Carvalho DD. Roulois D, et al. Among authors: de carvalho dd. Cell. 2015 Aug 27;162(5):961-73. doi: 10.1016/j.cell.2015.07.056. Cell. 2015. PMID: 26317465 Free PMC article.

10

Epigenetic therapy in immune-oncology.

Jones PA, Ohtani H, Chakravarthy A, De Carvalho DD. Jones PA, et al. Among authors: de carvalho dd. Nat Rev Cancer. 2019 Mar;19(3):151-161. doi: 10.1038/s41568-019-0109-9. Nat Rev Cancer. 2019. PMID: 30723290 Review.

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