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The role of LAT in increased CD8+ T cell exhaustion in trigeminal ganglia of mice latently infected with herpes simplex virus 1.
Allen SJ, Hamrah P, Gate D, Mott KR, Mantopoulos D, Zheng L, Town T, Jones C, von Andrian UH, Freeman GJ, Sharpe AH, BenMohamed L, Ahmed R, Wechsler SL, Ghiasi H. Allen SJ, et al. Among authors: jones c. J Virol. 2011 May;85(9):4184-97. doi: 10.1128/JVI.02290-10. Epub 2011 Feb 9. J Virol. 2011. PMID: 21307196 Free PMC article.
A protein encoded by the latency-related gene of bovine herpesvirus 1 is expressed in trigeminal ganglionic neurons of latently infected cattle and interacts with cyclin-dependent kinase 2 during productive infection.
Jiang Y, Hossain A, Winkler MT, Holt T, Doster A, Jones C. Jiang Y, et al. Among authors: jones c. J Virol. 1998 Oct;72(10):8133-42. doi: 10.1128/JVI.72.10.8133-8142.1998. J Virol. 1998. PMID: 9733854 Free PMC article.
During acute infection of trigeminal ganglia or following dexamethasone-induced reactivation, BHV-1 induces expression of cyclin A in neurons (L. M. Schang, A. Hossain, and C. Jones, J. Virol. 70:3807-3814, 1996). Expression of S-phase regulatory proteins (cyclin A, …
During acute infection of trigeminal ganglia or following dexamethasone-induced reactivation, BHV-1 induces expression of cyclin A in neuron …
Persistence and reactivation of bovine herpesvirus 1 in the tonsils of latently infected calves.
Winkler MT, Doster A, Jones C. Winkler MT, et al. Among authors: jones c. J Virol. 2000 Jun;74(11):5337-46. doi: 10.1128/jvi.74.11.5337-5346.2000. J Virol. 2000. PMID: 10799611 Free PMC article.
Our previous results concluded that CD4(+) T cells in the tonsil and other adjacent lymph nodes are infected and undergo apoptosis during acute infection (M. T. Winkler, A. Doster, and C. Jones, J. Virol. 73:8657-8668, 1999). To test whether BHV-1 persisted in lymph …
Our previous results concluded that CD4(+) T cells in the tonsil and other adjacent lymph nodes are infected and undergo apoptosis during ac …
Region of herpes simplex virus type 1 latency-associated transcript sufficient for wild-type spontaneous reactivation promotes cell survival in tissue culture.
Inman M, Perng GC, Henderson G, Ghiasi H, Nesburn AB, Wechsler SL, Jones C. Inman M, et al. Among authors: jones c. J Virol. 2001 Apr;75(8):3636-46. doi: 10.1128/JVI.75.8.3636-3646.2001. J Virol. 2001. PMID: 11264353 Free PMC article.
We recently demonstrated that the LAT null mutant dLAT2903 induces increased levels of apoptosis in trigeminal ganglia of infected rabbits compared to LAT+ strains (G.-C. Perng, C. Jones, J. Ciacci-Zarella, M. Stone, G. Henderson, A. Yokht, S. M. Slanina, F. …
We recently demonstrated that the LAT null mutant dLAT2903 induces increased levels of apoptosis in trigeminal ganglia of infected rabbits c …
A gene capable of blocking apoptosis can substitute for the herpes simplex virus type 1 latency-associated transcript gene and restore wild-type reactivation levels.
Perng GC, Maguen B, Jin L, Mott KR, Osorio N, Slanina SM, Yukht A, Ghiasi H, Nesburn AB, Inman M, Henderson G, Jones C, Wechsler SL. Perng GC, et al. Among authors: jones c. J Virol. 2002 Feb;76(3):1224-35. doi: 10.1128/jvi.76.3.1224-1235.2002. J Virol. 2002. PMID: 11773398 Free PMC article.
A mutation in the latency-related gene of bovine herpesvirus 1 disrupts the latency reactivation cycle in calves.
Inman M, Lovato L, Doster A, Jones C. Inman M, et al. Among authors: jones c. J Virol. 2002 Jul;76(13):6771-9. doi: 10.1128/jvi.76.13.6771-6779.2002. J Virol. 2002. PMID: 12050390 Free PMC article.
When calves were infected with the LR mutant, a dramatic decrease (3 to 4 logs) in ocular, but not nasal, viral shedding occurred during acute infection relative to the wt or the LR-rescued virus (M. Inman, L. Lovato, A. Doster, and C. Jones, J. Virol. 75:8507-8515, …
When calves were infected with the LR mutant, a dramatic decrease (3 to 4 logs) in ocular, but not nasal, viral shedding occurred during acu …
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