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Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis.
Guo JY, Chen HY, Mathew R, Fan J, Strohecker AM, Karsli-Uzunbas G, Kamphorst JJ, Chen G, Lemons JM, Karantza V, Coller HA, Dipaola RS, Gelinas C, Rabinowitz JD, White E. Guo JY, et al. Among authors: mathew r. Genes Dev. 2011 Mar 1;25(5):460-70. doi: 10.1101/gad.2016311. Epub 2011 Feb 11. Genes Dev. 2011. PMID: 21317241 Free PMC article.
Autophagy suppresses tumorigenesis through elimination of p62.
Mathew R, Karp CM, Beaudoin B, Vuong N, Chen G, Chen HY, Bray K, Reddy A, Bhanot G, Gelinas C, Dipaola RS, Karantza-Wadsworth V, White E. Mathew R, et al. Cell. 2009 Jun 12;137(6):1062-75. doi: 10.1016/j.cell.2009.03.048. Cell. 2009. PMID: 19524509 Free PMC article.
Role of autophagy in suppression of inflammation and cancer.
White E, Karp C, Strohecker AM, Guo Y, Mathew R. White E, et al. Among authors: mathew r. Curr Opin Cell Biol. 2010 Apr;22(2):212-7. doi: 10.1016/j.ceb.2009.12.008. Epub 2010 Jan 6. Curr Opin Cell Biol. 2010. PMID: 20056400 Free PMC article. Review.
1,255 results