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Methylsulfonylnitrobenzoates, a new class of irreversible inhibitors of the interaction of the thyroid hormone receptor and its obligate coactivators that functionally antagonizes thyroid hormone.
Hwang JY, Huang W, Arnold LA, Huang R, Attia RR, Connelly M, Wichterman J, Zhu F, Augustinaite I, Austin CP, Inglese J, Johnson RL, Guy RK. Hwang JY, et al. Among authors: augustinaite i. J Biol Chem. 2011 Apr 8;286(14):11895-908. doi: 10.1074/jbc.M110.200436. Epub 2011 Feb 14. J Biol Chem. 2011. PMID: 21321127 Free PMC article.
A quantitative high-throughput screen identifies novel inhibitors of the interaction of thyroid receptor beta with a peptide of steroid receptor coactivator 2.
Johnson RL, Hwang JY, Arnold LA, Huang R, Wichterman J, Augustinaite I, Austin CP, Inglese J, Guy RK, Huang W. Johnson RL, et al. Among authors: augustinaite i. J Biomol Screen. 2011 Jul;16(6):618-27. doi: 10.1177/1087057111402199. Epub 2011 Apr 11. J Biomol Screen. 2011. PMID: 21482722 Free PMC article.
Quantification of the vitamin D receptor-coregulator interaction.
Teichert A, Arnold LA, Otieno S, Oda Y, Augustinaite I, Geistlinger TR, Kriwacki RW, Guy RK, Bikle DD. Teichert A, et al. Among authors: augustinaite i. Biochemistry. 2009 Feb 24;48(7):1454-61. doi: 10.1021/bi801874n. Biochemistry. 2009. PMID: 19183053 Free PMC article.