Descamps G - Search Results

1

Phase I study of the anti insulin-like growth factor 1 receptor (IGF-1R) monoclonal antibody, AVE1642, as single agent and in combination with bortezomib in patients with relapsed multiple myeloma.

Moreau P, Cavallo F, Leleu X, Hulin C, Amiot M, Descamps G, Facon T, Boccadoro M, Mignard D, Harousseau JL. Moreau P, et al. Among authors: descamps g. Leukemia. 2011 May;25(5):872-4. doi: 10.1038/leu.2011.4. Epub 2011 Feb 15. Leukemia. 2011. PMID: 21321571 Clinical Trial. No abstract available.

2

Bufalin Suppresses Head and Neck Cancer Development by Modulating Immune Responses and Targeting the β-Catenin Signaling Pathway.

Mhaidly N, Barake N, Trelcat A, Journe F, Saussez S, Descamps G. Mhaidly N, et al. Among authors: descamps g. Cancers (Basel). 2024 Aug 1;16(15):2739. doi: 10.3390/cancers16152739. Cancers (Basel). 2024. PMID: 39123466 Free PMC article.

3

CD45neg but not CD45pos human myeloma cells are sensitive to the inhibition of IGF-1 signaling by a murine anti-IGF-1R monoclonal antibody, mAVE1642.

Descamps G, Wuillème-Toumi S, Trichet V, Venot C, Debussche L, Hercend T, Collette M, Robillard N, Bataille R, Amiot M. Descamps G, et al. J Immunol. 2006 Sep 15;177(6):4218-23. doi: 10.4049/jimmunol.177.6.4218. J Immunol. 2006. PMID: 16951388

4

IL-21 stimulates human myeloma cell growth through an autocrine IGF-1 loop.

Ménoret E, Maïga S, Descamps G, Pellat-Deceunynck C, Fraslon C, Cappellano M, Moreau P, Bataille R, Amiot M. Ménoret E, et al. Among authors: descamps g. J Immunol. 2008 Nov 15;181(10):6837-42. doi: 10.4049/jimmunol.181.10.6837. J Immunol. 2008. PMID: 18981102

5

A humanised anti-IGF-1R monoclonal antibody (AVE1642) enhances Bortezomib-induced apoptosis in myeloma cells lacking CD45.

Descamps G, Gomez-Bougie P, Venot C, Moreau P, Bataille R, Amiot M. Descamps G, et al. Br J Cancer. 2009 Jan 27;100(2):366-9. doi: 10.1038/sj.bjc.6604839. Br J Cancer. 2009. PMID: 19165200 Free PMC article.

6

BH3-only protein Bik is involved in both apoptosis induction and sensitivity to oxidative stress in multiple myeloma.

Bodet L, Ménoret E, Descamps G, Pellat-Deceunynck C, Bataille R, Le Gouill S, Moreau P, Amiot M, Gomez-Bougie P. Bodet L, et al. Among authors: descamps g. Br J Cancer. 2010 Dec 7;103(12):1808-14. doi: 10.1038/sj.bjc.6605981. Epub 2010 Nov 9. Br J Cancer. 2010. PMID: 21063407 Free PMC article.

7

ABT-737 is highly effective against molecular subgroups of multiple myeloma.

Bodet L, Gomez-Bougie P, Touzeau C, Dousset C, Descamps G, Maïga S, Avet-Loiseau H, Bataille R, Moreau P, Le Gouill S, Pellat-Deceunynck C, Amiot M. Bodet L, et al. Among authors: descamps g. Blood. 2011 Oct 6;118(14):3901-10. doi: 10.1182/blood-2010-11-317438. Epub 2011 Aug 11. Blood. 2011. PMID: 21835956 Free article.

8

The cap-translation inhibitor 4EGI-1 induces apoptosis in multiple myeloma through Noxa induction.

Descamps G, Gomez-Bougie P, Tamburini J, Green A, Bouscary D, Maïga S, Moreau P, Le Gouill S, Pellat-Deceunynck C, Amiot M. Descamps G, et al. Br J Cancer. 2012 May 8;106(10):1660-7. doi: 10.1038/bjc.2012.139. Epub 2012 Apr 17. Br J Cancer. 2012. PMID: 22510748 Free PMC article.

9

Cell death via DR5, but not DR4, is regulated by p53 in myeloma cells.

Surget S, Chiron D, Gomez-Bougie P, Descamps G, Ménoret E, Bataille R, Moreau P, Le Gouill S, Amiot M, Pellat-Deceunynck C. Surget S, et al. Among authors: descamps g. Cancer Res. 2012 Sep 1;72(17):4562-73. doi: 10.1158/0008-5472.CAN-12-0487. Epub 2012 Jun 27. Cancer Res. 2012. PMID: 22738917

10

Autocrine insulin-like growth factor 1 and stem cell factor but not interleukin 6 support self-renewal of human myeloma cells.

Chiron D, Maïga S, Surget S, Descamps G, Gomez-Bougie P, Traore S, Robillard N, Moreau P, Le Gouill S, Bataille R, Amiot M, Pellat-Deceunynck C. Chiron D, et al. Among authors: descamps g. Blood Cancer J. 2013 Jun 7;3(6):e120. doi: 10.1038/bcj.2013.18. Blood Cancer J. 2013. PMID: 23749045 Free PMC article.

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